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IHC (Immunohistochemistry)
(Anti-FSD2 / Frizzled 2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit FSD2 / Frizzled 2 Polyclonal Antibody | anti-FZD2 antibody
Rabbit Polyclonal to Human FSD2 / Frizzled 2
Gene Names
FZD2; Fz2; fz-2; fzE2; hFz2
Reactivity
Bovine, Dog, Hamster, Horse, Human, Mouse, Pig, RatPredicted Reactivity: Rabbit, Sheep (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
FSD2 / Frizzled 2, Antibody; Rabbit Polyclonal to Human FSD2 / Frizzled 2; Anti-FSD2 / Frizzled 2 Antibody (Extracellular Domain) IHC-plus; Dfrizzled2; Fz2; Frizzled family receptor 2; Frizzled-2; HFz2; Frizzled homolog 2; Fz-2; FzE2; Mfz10; Rfz2; Frizzled 2; Human FSD2; anti-FZD2 antibody
Host
Rabbit
Reactivity
Bovine, Dog, Hamster, Horse, Human, Mouse, Pig, Rat
Predicted Reactivity: Rabbit, Sheep (at least 90% immunogen sequence identity)
Predicted Reactivity: Rabbit, Sheep (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human Frizzled 2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FZD7 (67%), OR1A2 (56%), NFATC2 (50%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
565
Applicable Applications for anti-FZD2 antibody
IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from 3rd extracellular domain of human Frizzled 2. Percent identity with other species by BLAST analysis: Human, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Pig (100%); Sheep, Rabbit (94%); Opossum (89%).
Immunogen Type
Synthetic peptide
Immunogen
FSD2 / Frizzled 2 antibody was raised against synthetic 18 amino acid peptide from 3rd extracellular domain of human Frizzled 2. Percent identity with other species by BLAST analysis: Human, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Pig (100%); Sheep, Rabbit (94%); Opossum (89%); Turkey, Chicken, Platypus, Lizard, Xenopus (83%).
Antigen Modification
Extracellular Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
IHC (Immunohistochemistry)
(Anti-FSD2 / Frizzled 2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-FSD2 / Frizzled 2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-Frizzled 2 antibody IHC of human fetal kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-Frizzled 2 antibody IHC of human fetal kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemisry)
(Anti-FSD2 / Frizzled 2 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemisry)
(Anti-FSD2 / Frizzled 2 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohiostchemistry)
(Anti-FSD2 / Frizzled 2 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohiostchemistry)
(Anti-FSD2 / Frizzled 2 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-FSD2 / Frizzled 2 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-FSD2 / Frizzled 2 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-FZD2 antibody
FZD2 is a Frizzled Receptor that mediates Wnt signaling, which is required for proper axis development in the embryo. FZD2 is developmentally regulated. Studies of rat FZD2 indicate that the protein signals through a calcium-releasing pathway and that FDZ2 expression modulates protein kinase C (PKC) localization and stimulates PKC activity in vitro. Increased levels of FZD2 mRNA have been observed in primary gastric cancer and in head and neck squamous carcinoma and gastric cancer cell lines.
Product Categories/Family for anti-FZD2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63,554 Da
NCBI Official Full Name
frizzled-2
NCBI Official Synonym Full Names
frizzled class receptor 2
NCBI Official Symbol
FZD2
NCBI Official Synonym Symbols
Fz2; fz-2; fzE2; hFz2
NCBI Protein Information
frizzled-2; frizzled homolog 2; frizzled family receptor 2; frizzled 2, seven transmembrane spanning receptor
UniProt Protein Name
Frizzled-2
UniProt Gene Name
FZD2
UniProt Synonym Gene Names
Fz-2; hFz2
UniProt Entry Name
FZD2_HUMAN
Similar Products
Product Notes
The FZD2 fzd2 (Catalog #AAA51477) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human FSD2 / Frizzled 2 reacts with Bovine, Dog, Hamster, Horse, Human, Mouse, Pig, Rat Predicted Reactivity: Rabbit, Sheep (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's FSD2 / Frizzled 2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the FZD2 fzd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FSD2 / Frizzled 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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