IHC (Immunohiostchemistry)
(G3BP1 Antibody (C-term) (AAA283835)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of G3BP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit G3BP1 Polyclonal Antibody | anti-G3BP1 antibody
G3BP1 Antibody (C-term)
Gene Names
G3BP1; G3BP; HDH-VIII
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
G3BP1, Antibody; G3BP1 Antibody (C-term); Ras GTPase-activating protein-binding protein 1; G3BP-1; ATP-dependent DNA helicase VIII; hDH VIII; GAP SH3 domain-binding protein 1; G3BP1; G3BP; anti-G3BP1 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This G3BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the C-terminal region of human G3BP1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.47 (varies by lot)
Sequence Positions
401-430
Sequence Length
122
Applicable Applications for anti-G3BP1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(G3BP1 Antibody (C-term) (AAA283835)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of G3BP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(G3BP1 Antibody (C-term) (AAA283835)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of G3BP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(G3BP1 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the G3BP1 antibody detected the G3BP1 protein (arrow).)
WB (Western Blot)
(G3BP1 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the G3BP1 antibody detected the G3BP1 protein (arrow).)
Related Product Information for anti-G3BP1 antibody
This gene encodes one of the DNA-unwinding enzymes which
prefers partially unwound 3'-tailed substrates and can also unwind
partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion.
This enzyme is a member of the heterogeneous nuclear RNA-binding
proteins and is also an element of the Ras signal transduction
pathway. It binds specifically to the Ras-GTPase-activating protein
by associating with its SH3 domain. Several alternatively spliced
transcript variants of this gene have been described, but the
full-length nature of some of these variants has not been
determined.
prefers partially unwound 3'-tailed substrates and can also unwind
partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion.
This enzyme is a member of the heterogeneous nuclear RNA-binding
proteins and is also an element of the Ras signal transduction
pathway. It binds specifically to the Ras-GTPase-activating protein
by associating with its SH3 domain. Several alternatively spliced
transcript variants of this gene have been described, but the
full-length nature of some of these variants has not been
determined.
References
Gao, X., et al. FEBS Lett. 584(16):3525-3532(2010)
Ortega, A.D., et al. J. Cell. Sci. 123 (PT 16), 2685-2696 (2010) :
Hinton, S.D., et al. Biochem. J. 427(3):349-357(2010)
Shim, J.H., et al. Cancer Prev Res (Phila) 3(5):670-679(2010)
Zhang, H.Z., et al. World J. Gastroenterol. 13(30):4126-4130(2007)
Ortega, A.D., et al. J. Cell. Sci. 123 (PT 16), 2685-2696 (2010) :
Hinton, S.D., et al. Biochem. J. 427(3):349-357(2010)
Shim, J.H., et al. Cancer Prev Res (Phila) 3(5):670-679(2010)
Zhang, H.Z., et al. World J. Gastroenterol. 13(30):4126-4130(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52164
NCBI Official Full Name
ras GTPase-activating protein-binding protein 1
NCBI Official Synonym Full Names
GTPase activating protein (SH3 domain) binding protein 1
NCBI Official Symbol
G3BP1
NCBI Official Synonym Symbols
G3BP; HDH-VIII
NCBI Protein Information
ras GTPase-activating protein-binding protein 1
UniProt Protein Name
Ras GTPase-activating protein-binding protein 1
UniProt Gene Name
G3BP1
UniProt Synonym Gene Names
G3BP; G3BP-1; hDH VIII
UniProt Entry Name
G3BP1_HUMAN
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Product Notes
The G3BP1 g3bp1 (Catalog #AAA283835) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 401-430. The G3BP1 Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's G3BP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the G3BP1 g3bp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "G3BP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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