WB (Western Blot)
Rabbit GATA1 Polyclonal Antibody | anti-GATA1 antibody
Rabbit anti GATA1 (pS142) Polyclonal Antibody
Gene Names
GATA1; GF1; GF-1; NFE1; XLTT; ERYF1; NF-E1; XLANP; XLTDA; GATA-1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry, ELISA
Purity
Purified by site-modified Epitope Affinity Purification.
Synonyms
GATA1, Antibody; Rabbit anti GATA1 (pS142) Polyclonal Antibody; GATA binding protein 1; globin transcription factor 1; anti-GATA1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody recognizes GATA1 with the phosphorylation site Ser142. It does not cross-react with non-phosphospecific peptide.
Purity/Purification
Purified by site-modified Epitope Affinity Purification.
Form/Format
Supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer.
Sequence Length
335
Applicable Applications for anti-GATA1 antibody
WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), ELISA
Positive Control
K562
Cellular Location
Nucleus.
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20°C to -70°C. The antibodies can be stored at 2-8°C for three months without detectable loss of activity. Avoid repeated freezing-thawing cycles.
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-GATA1 antibody
Antigen Preparation: A synthetic phosphor-peptide -- TLKTERLSPDLLTLG corresponding to residues surrounding Ser142 of human GATA1. It is identical among human, mouse and rat species.
Background: GATA1 belongs to the GATA family of transcriptiion factors.The proteins comprise a group of transcription factors that are related by the presence of conserved zinc finger DNA binding domains, which bind directly to the nucleotide sequence core element GATA. There are six vertebrate GATA proteins, designated GATA-1 to GATA-6. GATA-1 is the foundng member of the GATA family and is required for erythroid and megakaryocytic cell development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in GATA-1 have been linked to many human diseases, including acute megakaryoblastic leukemia in Down syndrome children (DS-AMKL), X-linked thrombocytopenia, and gray platelet syndrome.
Background: GATA1 belongs to the GATA family of transcriptiion factors.The proteins comprise a group of transcription factors that are related by the presence of conserved zinc finger DNA binding domains, which bind directly to the nucleotide sequence core element GATA. There are six vertebrate GATA proteins, designated GATA-1 to GATA-6. GATA-1 is the foundng member of the GATA family and is required for erythroid and megakaryocytic cell development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in GATA-1 have been linked to many human diseases, including acute megakaryoblastic leukemia in Down syndrome children (DS-AMKL), X-linked thrombocytopenia, and gray platelet syndrome.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
~45 kDa
NCBI Official Full Name
GATA1 protein
NCBI Official Synonym Full Names
GATA binding protein 1
NCBI Official Symbol
GATA1
NCBI Official Synonym Symbols
GF1; GF-1; NFE1; XLTT; ERYF1; NF-E1; XLANP; XLTDA; GATA-1
NCBI Protein Information
erythroid transcription factor
UniProt Protein Name
Erythroid transcription factor
UniProt Gene Name
GATA1
UniProt Synonym Gene Names
ERYF1; GF1; GATA-1; GF-1
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Product Notes
The GATA1 gata1 (Catalog #AAA71302) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti GATA1 (pS142) Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GATA1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the GATA1 gata1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GATA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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