IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using GCK Polyclonal Antibody at dilution 1:20)
Rabbit GCK Polyclonal Antibody | anti-GCK antibody
GCK Polyclonal Antibody
Gene Names
GCK; GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Antigen affinity purification
Synonyms
GCK, Antibody; GCK Polyclonal Antibody; GK, GLK, HK4, HHF3, HKIV, HXKP, LGLK, MODY2, FGQTL3; anti-GCK antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
0.6mg/mL (varies by lot)
Sequence Length
464
Applicable Applications for anti-GCK antibody
IHC (Immunohistochemistry), ELISA
Immunogen
Synthetic peptide of human GCK
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using GCK Polyclonal Antibody at dilution 1:20)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using GCK Polyclonal Antibody at dilution 1:20)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using GCK Polyclonal Antibody at dilution 1:20)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using GCK Polyclonal Antibody at dilution 1:20)
Related Product Information for anti-GCK antibody
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
Product Categories/Family for anti-GCK antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,035 Da
NCBI Official Full Name
glucokinase isoform 3
NCBI Official Synonym Full Names
glucokinase (hexokinase 4)
NCBI Official Symbol
GCK
NCBI Official Synonym Symbols
GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3
NCBI Protein Information
glucokinase; ATP:D-hexose 6-phosphotransferase; HK IV; hexokinase D, pancreatic isozyme; hexokinase type IV; hexokinase-4; hexokinase-D
UniProt Protein Name
Glucokinase
UniProt Gene Name
GCK
UniProt Synonym Gene Names
HK IV; HK4
UniProt Entry Name
HXK4_HUMAN
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Product Notes
The GCK gck (Catalog #AAA167841) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GCK Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GCK can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the GCK gck for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GCK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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