IHC (Immunohistochemisry)
(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with GJB6 Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Rabbit anti-Human GJB6 Polyclonal Antibody | anti-GJB6 antibody
GJB6 Antibody (N-term)
Gene Names
GJB6; ED2; EDH; HED; CX30; HED2; DFNA3; ECTD2; DFNA3B; DFNB1B
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GJB6, Antibody; GJB6 Antibody (N-term); Gap junction beta-6 protein; Connexin-30; Cx30; GJB6; anti-GJB6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
This GJB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-117 amino acids from the N-terminal region of human GJB6.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Sequence Positions
87-117
Sequence Length
261
Applicable Applications for anti-GJB6 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Cellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with GJB6 Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohistochemisry)
(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with GJB6 Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
WB (Western Blot)
(Western blot analysis of GJB6 (arrow) using rabbit polyclonal GJB6 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GJB6gene (Lane 2) (Origene Technologies).)
WB (Western Blot)
(Western blot analysis of GJB6 (arrow) using rabbit polyclonal GJB6 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GJB6gene (Lane 2) (Origene Technologies).)
Product Categories/Family for anti-GJB6 antibody
References
Beltramello, M., et al., Biochem. Biophys. Res. Commun. 305(4):1024-1033 (2003).
Common, J.E., et al., Biochem. Biophys. Res. Commun. 298(5):651-656 (2002).
Smith, F.J., et al., J. Invest. Dermatol. 118(3):530-532 (2002).
del Castillo, I., et al., N. Engl. J. Med. 346(4):243-249 (2002).
Pallares-Ruiz, N., et al., Eur. J. Hum. Genet. 10(1):72-76 (2002).
Common, J.E., et al., Biochem. Biophys. Res. Commun. 298(5):651-656 (2002).
Smith, F.J., et al., J. Invest. Dermatol. 118(3):530-532 (2002).
del Castillo, I., et al., N. Engl. J. Med. 346(4):243-249 (2002).
Pallares-Ruiz, N., et al., Eur. J. Hum. Genet. 10(1):72-76 (2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30387 (Calculated)
NCBI Official Full Name
gap junction beta-6 protein
NCBI Official Synonym Full Names
gap junction protein, beta 6, 30kDa
NCBI Official Symbol
GJB6
NCBI Official Synonym Symbols
ED2; EDH; HED; CX30; HED2; DFNA3; ECTD2; DFNA3B; DFNB1B
NCBI Protein Information
gap junction beta-6 protein
UniProt Protein Name
Gap junction beta-6 protein
UniProt Gene Name
GJB6
UniProt Synonym Gene Names
Cx30
UniProt Entry Name
CXB6_HUMAN
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Product Notes
The GJB6 gjb6 (Catalog #AAA288873) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 87-117. The GJB6 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GJB6 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the GJB6 gjb6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GJB6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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