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product-image-AAA29941_FCM6.jpg FCM (Flow Cytometry) (Flow cytometric analysis of A549 cells with GLUR antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.)

Rabbit anti-Human, Rat GLUR Polyclonal Antibody | anti-GLUR antibody

GLUR Antibody

Gene Names
GSR; HEL-75
Reactivity
Human, Rat
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry
Purity
Protein affinity purified
Synonyms
GLUR, Antibody; GLUR Antibody; GLR1 antibody; GLUR antibody; Glutathione reductase antibody; Glutathione reductase mitochondrial antibody; Glutathione reductase; mitochondrial antibody; GR antibody; Gr1 antibody; GRase antibody; GRD 1 antibody; GRD1 antibody; GSHR_HUMAN antibody; GSR antibody; MGC78522 antibody; anti-GLUR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Purity/Purification
Protein affinity purified
Form/Format
1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-GLUR antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Flow Cytometry (FC)
Application Notes
WB: 1:1000-1:2000
IHC: 1:50-1:200
ICC: 1:50-1:200
FC: 1:50-1:100
Immunogen
Recombinant protein within human GLUR 260-450 aa.
Preparation and Storage
Store at -20°C.

FCM (Flow Cytometry)

(Flow cytometric analysis of A549 cells with GLUR antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.)

product-image-AAA29941_FCM6.jpg FCM (Flow Cytometry) (Flow cytometric analysis of A549 cells with GLUR antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.)

ICC (Immunocytochemistry)

(ICC staining GLUR in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

product-image-AAA29941_ICC5.jpg ICC (Immunocytochemistry) (ICC staining GLUR in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human thyroid gland tissue using anti-GLUR antibody. Counter stained with hematoxylin.)

product-image-AAA29941_IHC4.jpg IHC (Immunohistochemistry) (Immunohistochemical analysis of paraffin-embedded human thyroid gland tissue using anti-GLUR antibody. Counter stained with hematoxylin.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-GLUR antibody. Counter stained with hematoxylin.)

product-image-AAA29941_IHC3.jpg IHC (Immunohistochemistry) (Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-GLUR antibody. Counter stained with hematoxylin.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-GLUR antibody. Counter stained with hematoxylin.)

product-image-AAA29941_IHC2.jpg IHC (Immunohistochemistry) (Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-GLUR antibody. Counter stained with hematoxylin.)

WB (Western Blot)

(Western blot analysis of GLUR on different lysates using anti-GLUR antibody at 1/2,000 dilution. Positive control�� Lane1: A549 Lane2: Rat liver tissue)

product-image-AAA29941_WB.jpg WB (Western Blot) (Western blot analysis of GLUR on different lysates using anti-GLUR antibody at 1/2,000 dilution. Positive control�� Lane1: A549 Lane2: Rat liver tissue)
Related Product Information for anti-GLUR antibody
Glutathione plays a key role in maintaining proper function and preventing oxidative stress in human cells. It can act as a scavenger for hydroxyl radicals, singlet oxygen, and various electrophiles. Reduced glutathione reduces the oxidized form of the enzyme glutathione peroxidase, which in turn reduces hydrogen peroxide (H2O2), a dangerously reactive species within the cell. In addition, it plays a key role in the metabolism and clearance of xenobiotics, acts as a cofactor in certain detoxifying enzymes, participates in transport, and regenerates antioxidants such and Vitamins E and C to their reactive forms. The ratio of GSSG/GSH present in the cell is a key factor in properly maintaining the oxidative balance of the cell, that is, it is critical that the cell maintains high levels of the reduced glutathione and a low level of the oxidized Glutathione disulfide. This narrow balance is maintained by glutathione reductase, which catalyzes the reduction of GSSG to GSH.
Product Categories/Family for anti-GLUR antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated MW: 56 kDa
NCBI Official Full Name
glutathione reductase, mitochondrial isoform 1
NCBI Official Synonym Full Names
glutathione reductase
NCBI Official Symbol
GSR
NCBI Official Synonym Symbols
HEL-75
NCBI Protein Information
glutathione reductase, mitochondrial; GR; GRase; epididymis luminal protein 75
UniProt Protein Name
Glutathione reductase, mitochondrial
UniProt Gene Name
GSR
UniProt Synonym Gene Names
GLUR; GRD1; GR; GRase
UniProt Entry Name
GSHR_HUMAN

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Product Notes

The GLUR gsr (Catalog #AAA29941) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GLUR Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GLUR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Flow Cytometry (FC). WB: 1:1000-1:2000 IHC: 1:50-1:200 ICC: 1:50-1:200 FC: 1:50-1:100. Researchers should empirically determine the suitability of the GLUR gsr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GLUR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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