Rabbit anti-Human GLUT-3 Polyclonal Antibody | anti-GLUT-3 antibody

Rabbit anti GLUT-3 Polyclonal Antibody

Cat. Num. AAA71311

• Gene Names: Slc2a3; Glut3; C78366; Glut-3; AA408729; AL023014; AL024341; AU040424
• Reactivity: Human
• Applications: Western Blot, Immunoprecipitation, Immunohistochemistry, ELISA
• Purity: Purified by Epitope Affinity Purification
• Synonyms: GLUT-3, Antibody; Rabbit anti GLUT-3 Polyclonal Antibody; Glucose transporter type 1; GLUT1; SLC2A3; anti-GLUT-3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This antbody recognizes human GLUT-3. The other species not tested.
• Purity/Purification: Purified by Epitope Affinity Purification
• Form/Format: Supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Sequence Length: 121

• Applicable Applications for anti-GLUT-3 antibody: WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), ELISA
• Antigen Preparation: A synthetic peptide corresponding to the C-terminus of GLUT-3
• Positive Control: Kidney Tissue
• Cellular Location: Cell Membrane
• Preparation and Storage: The antibodies are stable for 12 months from date of receipt when stored at -20°C. The antibodies can be stored at 2°C - 8°C for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

IHC (Immunohistochemistry)

(Immunohistochemistry: Human GIST carcinoma (FFPE) stained with Rabbit anti Glut-3 (Cat# ) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.)

Related Product Information for anti-GLUT-3 antibody

Background: The Glutamate receptors (GluR) are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. GluR constitutes the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR1-7, NMDA1-3, KAI-2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.

NCBI and Uniprot Product Information

• NCBI GI #: 871425
• NCBI GeneID: 20527
• UniProt Accession #: Q61607; P32037
• Molecular Weight: 49-52
• NCBI Official Full Name: Glut-3, partial
• NCBI Official Synonym Full Names: solute carrier family 2 (facilitated glucose transporter), member 3
• NCBI Official Symbol: Slc2a3
• NCBI Official Synonym Symbols: Glut3; C78366; Glut-3; AA408729; AL023014; AL024341; AU040424
• NCBI Protein Information: solute carrier family 2, facilitated glucose transporter member 3
• UniProt Protein Name: Glut-3 protein
• UniProt Gene Name: Slc2a3