IHC (Immunohiostchemistry)
(GMNN Antibody (Center Y111) IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GMNN Antibody (Center Y111) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit GMNN Polyclonal Antibody | anti-GMNN antibody
GMNN Antibody (Center Y111)
Gene Names
GMNN; Gem
Reactivity
Human (Predicted Reactivity: Mouse)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GMNN, Antibody; GMNN Antibody (Center Y111); Geminin; GMNN; anti-GMNN antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GMNN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-123 amino acids from the Central region of human GMNN.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
96-123
Sequence Length
209
Applicable Applications for anti-GMNN antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(GMNN Antibody (Center Y111) IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GMNN Antibody (Center Y111) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(GMNN Antibody (Center Y111) IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GMNN Antibody (Center Y111) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of GMNN Antibody (Center Y111) in HepG2 cell line lysates (35ug/lane).GMNN (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of GMNN Antibody (Center Y111) in HepG2 cell line lysates (35ug/lane).GMNN (arrow) was detected using the purified Pab.)
Related Product Information for anti-GMNN antibody
GMNN inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
Product Categories/Family for anti-GMNN antibody
References
De Marco, V., et al. Proc. Natl. Acad. Sci. U.S.A. 106(47):19807-19812(2009)
Zhu, W., et al. Cancer Res. 69(11):4870-4877(2009)
Lu, F., et al. Biol. Cell 101(5):273-285(2009)
Zhu, W., et al. Cancer Res. 69(11):4870-4877(2009)
Lu, F., et al. Biol. Cell 101(5):273-285(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23565
NCBI Official Full Name
geminin
NCBI Official Synonym Full Names
geminin, DNA replication inhibitor
NCBI Official Symbol
GMNN
NCBI Official Synonym Symbols
Gem
NCBI Protein Information
geminin
UniProt Protein Name
Geminin
UniProt Gene Name
GMNN
UniProt Entry Name
GEMI_HUMAN
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Product Notes
The GMNN gmnn (Catalog #AAA284398) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 96-123. The GMNN Antibody (Center Y111) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's GMNN can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the GMNN gmnn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GMNN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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