IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using Grik4 antibody at 2.5 ug/mL.)
Rabbit Grik4 Polyclonal Antibody | anti-Grik4 antibody
Grik4 Antibody
Gene Names
GRIK4; KA1; EAA1; GRIK; GluK4
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Grik4, Antibody; Grik4 Antibody; Glutamate receptor ionotropic kainate 4 precursor, Glutamate receptor KA-1, Excitatory amino acid receptor 1, EAA1; anti-Grik4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
956
Applicable Applications for anti-Grik4 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 19 amino acid peptide near the carboxy terminus of the human Grik4.
Target Name
Grik4
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using Grik4 antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using Grik4 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of Grik4 in rat brain lysate with Grik4 antibody at (A) 0.5 (B) 1 and (C) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of Grik4 in rat brain lysate with Grik4 antibody at (A) 0.5 (B) 1 and (C) 2 ug/mL.)
Related Product Information for anti-Grik4 antibody
Grik4 codes for the KA1 subunit of kainate-type ionotropic glutamate receptors which are critical regulators of network activity that act by modifying neuronal excitability, directly and indirectly, through GABAergic interneurons. Five subunits can assemble to form kainate receptors (KARs): GluR5 (coded by Grik1), GluR6 (coded by Grik2), and GluR7 (coded by Grik3) are the low-affinity subunits, and KA1 and KA2 are the high-affinity subunits. In the adult brain, KARs are located pre- and postsynaptically on pyramidal cells and on interneurons. Kainate receptors on GABA-containing interneurons enhance GABA release and thereby downregulate glutamatergic signaling. KARs have been implicated in numerous psychiatric disorders. Case control studies show significant association of Grik4 with both schizophrenia and bipolar disorder.
Product Categories/Family for anti-Grik4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
107,246 Da
NCBI Official Full Name
glutamate receptor ionotropic, kainate 4 isoform 1
NCBI Official Synonym Full Names
glutamate receptor, ionotropic, kainate 4
NCBI Official Symbol
GRIK4
NCBI Official Synonym Symbols
KA1; EAA1; GRIK; GluK4
NCBI Protein Information
glutamate receptor ionotropic, kainate 4
UniProt Protein Name
Glutamate receptor ionotropic, kainate 4
UniProt Gene Name
GRIK4
UniProt Synonym Gene Names
GRIK; GluK4; EAA1; KA1
UniProt Entry Name
GRIK4_HUMAN
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Product Notes
The Grik4 grik4 (Catalog #AAA307812) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Grik4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Grik4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Grik4 grik4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Grik4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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