Rabbit Grik5 Polyclonal Antibody | anti-GRIK5 antibody

Grik5 Antibody

Cat. Num. AAA39508

• Gene Names: GRIK5; KA2; EAA2; GRIK2; GluK5
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: Grik5 Antibody is affinity chromatography purified via peptide column.
• Synonyms: Grik5, Antibody; Grik5 Antibody; Grik5; KA2; EAA2; GRIK2; GluK5; Glutamate receptor ionotropic; kainate 5; Excitatory amino acid receptor 2; glutamate receptor, ionotropic, kainate 5; anti-GRIK5 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This Grik5 antibody does not cross-react with Grik4.
• Purity/Purification: Grik5 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 980

• Applicable Applications for anti-GRIK5 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: Grik5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Grik5.
• Buffer: Grik5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: Grik5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of Grik5 in Human Brain cells with Grik5 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemical staining of human brain tissue using Grik5 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of Grik5 in human brain tissue lysate with Grik5 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.)

Related Product Information for anti-GRIK5 antibody

Grik5 Antibody: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik5, also known as kainate-preferring glutamate recptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (also known as KA1). Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2. In Grik2- but not Grik1-null mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface.

NCBI and Uniprot Product Information

• NCBI GI #: 29029597
• NCBI GeneID: 2901
• NCBI Accession #: NP_002079
• NCBI GenBank Nucleotide #: NM_002088.4
• UniProt Accession #: Q16478; Q8WWG8
• Molecular Weight: 109,658 Da
• NCBI Official Full Name: glutamate receptor ionotropic, kainate 5 isoform 2
• NCBI Official Synonym Full Names: glutamate receptor, ionotropic, kainate 5
• NCBI Official Symbol: GRIK5
• NCBI Official Synonym Symbols: KA2; EAA2; GRIK2; GluK5
• NCBI Protein Information: glutamate receptor ionotropic, kainate 5; glutamate receptor KA2; excitatory amino acid receptor 2
• UniProt Protein Name: Glutamate receptor ionotropic, kainate 5
• UniProt Gene Name: GRIK5
• UniProt Synonym Gene Names: GRIK2; GluK5; EAA2; KA2
• UniProt Entry Name: GRIK5_HUMAN