IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Mouse lung tissue with GSK3beta Polyclonal Antibody.)
Rabbit anti-Mouse, Rat GSK3beta Polyclonal Antibody | anti-GSK3beta antibody
GSK3beta Polyclonal Antibody
Reactivity
Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Purification
Synonyms
GSK3beta, Antibody; GSK3beta Polyclonal Antibody; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B; anti-GSK3beta antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Concentration
1mg/mL (varies by lot)
Sequence Length
420
Applicable Applications for anti-GSK3beta antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant Protein
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Mouse lung tissue with GSK3beta Polyclonal Antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Mouse lung tissue with GSK3beta Polyclonal Antibody.)
WB (Western Blot)
(Western Blot analysis of 1) Mouse brain, 2) Mouse heart, 3) Rat brain, 4) Rat heart using GSK3beta Polyclonal Antibody at dilution of 1:20000.)
WB (Western Blot)
(Western Blot analysis of 1) Mouse brain, 2) Mouse heart, 3) Rat brain, 4) Rat heart using GSK3beta Polyclonal Antibody at dilution of 1:20000.)
Related Product Information for anti-GSK3beta antibody
Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Phosphorylates MACF1 and this phosphorylation inhibits the binding of MACF1 to microtubules which is critical for its role in bulge stem cell migration and skin wound repair.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46kDa
NCBI Official Full Name
glycogen synthase kinase-3 beta isoform 2
NCBI Official Synonym Full Names
glycogen synthase kinase 3 beta
NCBI Official Symbol
GSK3B
NCBI Protein Information
glycogen synthase kinase-3 beta
UniProt Protein Name
Glycogen synthase kinase-3 beta
UniProt Gene Name
GSK3B
UniProt Synonym Gene Names
GSK-3 beta
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Product Notes
The GSK3beta gsk3b (Catalog #AAA173733) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GSK3beta Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GSK3beta can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GSK3beta gsk3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GSK3beta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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