Rabbit GSTM1 Polyclonal Antibody | anti-GSTM1 antibody

GSTM1 Polyclonal Antibody

Cat. Num. AAA179805

• Gene Names: Gstm1; Gstb1; Gstb-1
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Antigen Affinity Purification
• Synonyms: GSTM1, Antibody; GSTM1 Polyclonal Antibody; Glutathione S-transferase Mu 1; EC:2.5.1.18; GST 1-1; GST class-mu 1; Glutathione S-transferase GT8.7; pmGT10; Gstm1; anti-GSTM1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
• Concentration: 1mg/mL (varies by lot)

• Applicable Applications for anti-GSTM1 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Recombinant Mouse GSTM1 protein expressed by E coli
• Preparation and Storage: Store at -20 degree C Valid for 12 months. Avoid freeze/thaw cycles.

IF (Immunofluorescence)

(Immunofluorescence analysis of C6 cells using GSTM1 Polyclonal Antibody at dilution of 1:200)

IF (Immunofluorescence)

(Immunofluorescence analysis of NIH-3T3 cells using GSTM1 Polyclonal Antibody at dilution of 1:200)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded Human kidney using GSTM1 Polycloanl Antibody at dilution of 1:600)

WB (Western Blot)

(Western blot with GSTM1 Polyclonal antibody at dilution of 1:1000.lane 1:Rat heart)

Related Product Information for anti-GSTM1 antibody

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

Product Categories/Family for anti-GSTM1 antibody

Polyclonal Antibodies; Primary Antibodies; Polyclonal Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 6754084
• NCBI GeneID: 14862
• NCBI Accession #: NP_034488.1
• NCBI GenBank Nucleotide #: NM_010358.5
• UniProt Accession #: P10649
• NCBI Official Full Name: glutathione S-transferase Mu 1
• NCBI Official Synonym Full Names: glutathione S-transferase, mu 1
• NCBI Official Symbol: Gstm1
• NCBI Official Synonym Symbols: Gstb1; Gstb-1
• NCBI Protein Information: glutathione S-transferase Mu 1
• UniProt Protein Name: Glutathione S-transferase Mu 1
• UniProt Gene Name: Gstm1
• UniProt Entry Name: GSTM1_MOUSE