IHC (Immunohiostchemistry)
(Immunochemical staining of human HAS1 in human smooth muscle with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human HAS1 Polyclonal Antibody | anti-HAS1 antibody
Anti-HAS1 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
HAS1, Antibody; Anti-HAS1 Antibody, Rabbit Polyclonal; HAS1 Antibody, Rabbit PAb, Antigen Affinity Purified; Anti-HAS Antibody; anti-HAS1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human HAS1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-HAS1 antibody
IHC (Immunohistochemistry)
Immunogen
E Coli-derived Human HAS1 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human HAS1 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Immunochemical staining of human HAS1 in human smooth muscle with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohiostchemistry)
(Immunochemical staining of human HAS1 in human smooth muscle with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human HAS1 in human kidney with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human HAS1 in human kidney with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-HAS1 antibody
Hyaluronan is produced by three isoforms of hyaluronan synthase (HAS1, 2, and 3), these enzymes act on the inner face of plasma membrane and simultaneously translocate the growing polysaccharide through plasma membrane into extracellular space. The three members of the Has gene family are located in different chromosomes, expressed at specific stages of organ development and are subject to regulation by different hormonal and environmental signals. Although all three HAS isoforms resemble each other in protein sequence and function, some differences have been noted in enzyme stability, chain elongation rate, length of the chain, and substrate-dependent enzyme properties. Their subcellular locations are also slightly different.
References
Rilla K, et al. (2013) Hyaluronan synthase 1 (has1) requires higher cellular udp-glcnac concentration than has2 and has3. J Biol Chem 288 (8): 5973-5983.Golshani R, et al. (2007) Has1 expression in bladder cancer and its relation to urinary ha test. Int J Cancer 120 (8): 1712-1720.
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Product Notes
The HAS1 (Catalog #AAA256883) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-HAS1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HAS1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the HAS1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HAS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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