WB (Western Blot)
(Western blot analysis of HAT1 (arrow) using rabbit polyclonal HAT1 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HAT1 gene.)
Rabbit HAT1 Polyclonal Antibody | anti-HAT1 antibody
HAT1 Antibody (N-term)
Gene Names
HAT1; KAT1
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
HAT1, Antibody; HAT1 Antibody (N-term); Histone acetyltransferase type B catalytic subunit; Histone acetyltransferase 1; HAT1; KAT1; anti-HAT1 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This HAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human HAT1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
21-50
Sequence Length
334
Applicable Applications for anti-HAT1 antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of HAT1 (arrow) using rabbit polyclonal HAT1 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HAT1 gene.)
WB (Western Blot)
(Western blot analysis of HAT1 (arrow) using rabbit polyclonal HAT1 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HAT1 gene.)
WB (Western Blot)
(HAT1 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HAT1 antibody detected the HAT1 protein (arrow).)
WB (Western Blot)
(HAT1 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HAT1 antibody detected the HAT1 protein (arrow).)
Related Product Information for anti-HAT1 antibody
The protein encoded by this gene is a type B histone
acetyltransferase (HAT) that is involved in the rapid acetylation
of newly synthesized cytoplasmic histones, which are in turn
imported into the nucleus for de novo deposition onto nascent DNA
chains. Histone acetylation, particularly of histone H4, plays an
important role in replication-dependent chromatin assembly.
Specifically, this HAT can acetylate soluble but not nucleosomal
histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A
at lysine 5. Alternatively spliced transcript variants have been
identified for this gene.
acetyltransferase (HAT) that is involved in the rapid acetylation
of newly synthesized cytoplasmic histones, which are in turn
imported into the nucleus for de novo deposition onto nascent DNA
chains. Histone acetylation, particularly of histone H4, plays an
important role in replication-dependent chromatin assembly.
Specifically, this HAT can acetylate soluble but not nucleosomal
histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A
at lysine 5. Alternatively spliced transcript variants have been
identified for this gene.
References
Saade, E., et al. Proteomics 9(21):4934-4943(2009)
Miyamoto, N., et al. J. Biol. Chem. 283(26):18218-18226(2008)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Benson, L.J., et al. J. Biol. Chem. 282(2):836-842(2007)
Miyamoto, N., et al. J. Biol. Chem. 283(26):18218-18226(2008)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Benson, L.J., et al. J. Biol. Chem. 282(2):836-842(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49513
NCBI Official Full Name
histone acetyltransferase type B catalytic subunit
NCBI Official Synonym Full Names
histone acetyltransferase 1
NCBI Official Symbol
HAT1
NCBI Official Synonym Symbols
KAT1
NCBI Protein Information
histone acetyltransferase type B catalytic subunit
UniProt Protein Name
Histone acetyltransferase type B catalytic subunit
UniProt Gene Name
HAT1
UniProt Synonym Gene Names
KAT1
UniProt Entry Name
HAT1_HUMAN
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Product Notes
The HAT1 hat1 (Catalog #AAA288378) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 21-50. The HAT1 Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's HAT1 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the HAT1 hat1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HAT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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