IHC (Immunohistochemisry)
(Anti- HRG antibody, AAA46054, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
Rabbit Histidine-rich glycoprotein Polyclonal Antibody | anti-HRG antibody
Anti-HRG Antibody
Gene Names
HRG; HPRG; HRGP; THPH11
Reactivity
Human. No cross reactivity with other proteins.
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Histidine-rich glycoprotein, Antibody; Anti-HRG Antibody; DKFZp779H1622 antibody; Histidine proline rich glycoprotein antibody; Histidine rich glycoprotein antibody; HPRG antibody; HRGP antibody; Thrombophilia due to elevated HRG antibody; histidine-rich glycoprotein; anti-HRG antibody
Host
Rabbit
Reactivity
Human. No cross reactivity with other proteins.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
525
Applicable Applications for anti-HRG antibody
IHC (Immunohistochemistry), WB (Western Blot)
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
E.coli-derived human HRG recombinant protein (Position: V19-V200). Human HRG shares 71% and 69% amino acid (aa) sequences identity with mouse and rat HRG, respectively.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemisry)
(Anti- HRG antibody, AAA46054, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
IHC (Immunohistochemisry)
(Anti- HRG antibody, AAA46054, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
WB (Western Blot)
(Anti- HRG antibody, AAA46054, Western blottingAll lanes: Anti HRG (AAA46054) at 0.5ug/mlWB: Human Placenta Tissue Lysate at 50ugPredicted bind size: 60KDObserved bind size: 60KD)
WB (Western Blot)
(Anti- HRG antibody, AAA46054, Western blottingAll lanes: Anti HRG (AAA46054) at 0.5ug/mlWB: Human Placenta Tissue Lysate at 50ugPredicted bind size: 60KDObserved bind size: 60KD)
WB (Western Blot)
(Anti- HRG antibody, AAA46054, Western blottingAll lanes: Anti HRG (AAA46054) at 0.5ug/mlWB: Recombinant Human HRG Protein 0.5ngPredicted bind size: 40KDObserved bind size: 40KD)
WB (Western Blot)
(Anti- HRG antibody, AAA46054, Western blottingAll lanes: Anti HRG (AAA46054) at 0.5ug/mlWB: Recombinant Human HRG Protein 0.5ngPredicted bind size: 40KDObserved bind size: 40KD)
Related Product Information for anti-HRG antibody
Description: Rabbit IgG polyclonal antibody for Histidine-rich glycoprotein(HRG) detection. Tested with WB, IHC-P in Human.
Background: Histidine-rich glycoprotein (HRG) is a protein that in humans is encoded by the HRG gene. It is mapped to 3q27.3. HRG contains two cystatin-like domains and is located in plasma and platelets. The protein can bind heme, dyes and divalent metal ions. It also can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. HRG is thought to have multiple roles as a protein in the human blood, including roles in immunity, angiogenesis and coagulation.
Background: Histidine-rich glycoprotein (HRG) is a protein that in humans is encoded by the HRG gene. It is mapped to 3q27.3. HRG contains two cystatin-like domains and is located in plasma and platelets. The protein can bind heme, dyes and divalent metal ions. It also can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. HRG is thought to have multiple roles as a protein in the human blood, including roles in immunity, angiogenesis and coagulation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,578 Da
NCBI Official Full Name
histidine-rich glycoprotein
NCBI Official Synonym Full Names
histidine-rich glycoprotein
NCBI Official Symbol
HRG
NCBI Official Synonym Symbols
HPRG; HRGP; THPH11
NCBI Protein Information
histidine-rich glycoprotein; histidine-proline-rich glycoprotein
UniProt Protein Name
Histidine-rich glycoprotein
UniProt Gene Name
HRG
UniProt Synonym Gene Names
HPRG
UniProt Entry Name
HRG_HUMAN
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Product Notes
The HRG hrg (Catalog #AAA46054) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-HRG Antibody reacts with Human. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's Histidine-rich glycoprotein can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the HRG hrg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Histidine-rich glycoprotein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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