WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.)
Rabbit Hrs Polyclonal Antibody | anti-Hrs antibody
Hrs (phospho Tyr216) Polyclonal Antibody
Gene Names
HGS; HRS
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
Hrs, Antibody; Hrs (phospho Tyr216) Polyclonal Antibody; HGS; HRS; Hepatocyte growth factor-regulated tyrosine kinase substrate; Hrs; Protein pp110; anti-Hrs antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Applicable Applications for anti-Hrs antibody
WB (Western Blot)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.)
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.)
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.)
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.)
Related Product Information for anti-Hrs antibody
Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down- regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
86,192 Da
NCBI Official Full Name
hepatocyte growth factor-regulated tyrosine kinase substrate
NCBI Official Synonym Full Names
hepatocyte growth factor-regulated tyrosine kinase substrate
NCBI Official Symbol
HGS
NCBI Official Synonym Symbols
HRS
NCBI Protein Information
hepatocyte growth factor-regulated tyrosine kinase substrate; protein pp110; human growth factor-regulated tyrosine kinase substrate
UniProt Protein Name
Hepatocyte growth factor-regulated tyrosine kinase substrate
UniProt Gene Name
HGS
UniProt Synonym Gene Names
HRS
UniProt Entry Name
HGS_HUMAN
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Product Notes
The Hrs hgs (Catalog #AAA293900) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Hrs (phospho Tyr216) Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Hrs can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the Hrs hgs for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hrs, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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