IHC (Immunohistochemisry)
(Anti-HSD17B2 antibody, AAA44941, IHC(F)IHC(F): Human Placenta Tissue)
Rabbit anti-Human HSD17B2 Polyclonal Antibody | anti-HSD17B2 antibody
Anti-HSD17B2 antibody
Gene Names
HSD17B2; HSD17; SDR9C2; EDH17B2
Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
HSD17B2, Antibody; Anti-HSD17B2 antibody; Estradiol 17-beta-dehydrogenase 2; hydroxysteroid(17-beta) dehydrogenase 2; 17 beta HSD 2 antibody; 17-beta-HSD 2 antibody; 17-beta-hydroxysteroid dehydrogenase type 2 antibody; 20 alpha HSD antibody; 20 alpha hydroxysteroid dehydrogenase antibody; 20 alpha-hydroxysteroid dehydrogenase antibody; 20-alpha-HSD antibody; DHB2_HUMAN antibody; E2DH antibody; EDH17B2 antibody; Estradiol 17-beta-dehydrogenase 2 antibody; HSD17 antibody; Hsd17b2 antibody; Hydroxysteroid(17 beta) dehydrogenase 2 antibody; Microsomal 17 beta hydroxysteroid dehydrogenase antibody; Microsomal 17-beta-hydroxysteroid dehydrogenase antibody; SDR9C2 antibody; Testosterone 17 beta dehydrogenase antibody; Testosterone 17-beta-dehydrogenase antibody; anti-HSD17B2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
387
Applicable Applications for anti-HSD17B2 antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human HSD17B2 (373-387aa MPRALRMPNYKKKAT).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemisry)
(Anti-HSD17B2 antibody, AAA44941, IHC(F)IHC(F): Human Placenta Tissue)
IHC (Immunohistochemisry)
(Anti-HSD17B2 antibody, AAA44941, IHC(F)IHC(F): Human Placenta Tissue)
IHC (Immunohiostchemistry)
(Anti-HSD17B2 antibody, AAA44941, IHC(P)IHC(P): Human Placenta Tissue)
IHC (Immunohiostchemistry)
(Anti-HSD17B2 antibody, AAA44941, IHC(P)IHC(P): Human Placenta Tissue)
WB (Western Blot)
(Anti-HSD17B2 antibody, AAA44941, Western blottingAll lanes: Anti HSD17B2 (AAA44941) at 0.5ug/mlWB: Human Placenta Tissue Lysate at 50ugPredicted bind size: 43KDObserved bind size: 43KD)
WB (Western Blot)
(Anti-HSD17B2 antibody, AAA44941, Western blottingAll lanes: Anti HSD17B2 (AAA44941) at 0.5ug/mlWB: Human Placenta Tissue Lysate at 50ugPredicted bind size: 43KDObserved bind size: 43KD)
Related Product Information for anti-HSD17B2 antibody
Description: Rabbit IgG polyclonal antibody for Estradiol 17-beta-dehydrogenase 2(HSD17B2) detection. Tested with WB, IHC-P, IHC-F in Human.
Background: HSD17B2(17-BETA-HYDROXYSTEROID DEHYDROGENASE II), also called 17-BETA-HSD II, is an anzyme which have 387 amino acids with a predicted molecular weight of 42,782 and associate with the membranes of the endoplasmic reticulum. Its Cytogenetic location is 16q23.3. The type 2 enzyme was capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. HSD17B2 mRNA was detected in 18 of 42(43%) adenomas but not in prolactinomas. In the human endometrium, inactivation of 17-beta-estradiol to estrone is catalyzed by HSD17B2. And HSD17B2 activity distinguishing between disease-free and diseased endometria. HSD17B2 efficiently catalyzes the oxidative metabolism of androgens and estrogens, and it is expressed in a large series of human peripheral tissues. The previous paradigm that HSD17B2 activity in the endometrium is elevated during the secretory phase is confined to diseased endometrium but not to disease-free endometrium.
Background: HSD17B2(17-BETA-HYDROXYSTEROID DEHYDROGENASE II), also called 17-BETA-HSD II, is an anzyme which have 387 amino acids with a predicted molecular weight of 42,782 and associate with the membranes of the endoplasmic reticulum. Its Cytogenetic location is 16q23.3. The type 2 enzyme was capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. HSD17B2 mRNA was detected in 18 of 42(43%) adenomas but not in prolactinomas. In the human endometrium, inactivation of 17-beta-estradiol to estrone is catalyzed by HSD17B2. And HSD17B2 activity distinguishing between disease-free and diseased endometria. HSD17B2 efficiently catalyzes the oxidative metabolism of androgens and estrogens, and it is expressed in a large series of human peripheral tissues. The previous paradigm that HSD17B2 activity in the endometrium is elevated during the secretory phase is confined to diseased endometrium but not to disease-free endometrium.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
42,785 Da
NCBI Official Full Name
Estradiol 17-beta-dehydrogenase 2
NCBI Official Synonym Full Names
hydroxysteroid (17-beta) dehydrogenase 2
NCBI Official Symbol
HSD17B2
NCBI Official Synonym Symbols
HSD17; SDR9C2; EDH17B2
NCBI Protein Information
estradiol 17-beta-dehydrogenase 2; E2DH; 20-alpha-HSD; 17-beta-HSD 2; testosterone 17-beta-dehydrogenase; 20 alpha-hydroxysteroid dehydrogenase; 17-beta-hydroxysteroid dehydrogenase type 2; microsomal 17-beta-hydroxysteroid dehydrogenase; short chain dehydrogenase/reductase family 9C, member 2
UniProt Protein Name
Estradiol 17-beta-dehydrogenase 2
UniProt Gene Name
HSD17B2
UniProt Synonym Gene Names
EDH17B2; 17-beta-HSD 2; 20-alpha-HSD
UniProt Entry Name
DHB2_HUMAN
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Product Notes
The HSD17B2 hsd17b2 (Catalog #AAA44941) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-HSD17B2 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HSD17B2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the HSD17B2 hsd17b2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSD17B2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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