WB (Western Blot)
(Western Blot analysis of extracts from 293,3T3 and Hela cells using IGF-1R antibody)
Rabbit IGF-1R Polyclonal Antibody | anti-IGF-1R antibody
IGF-1R antibody
Gene Names
Igf1r; hyft; CD221; IGF-1R; D930020L01; A330103N21Rik
Applications
Western Blot, Immunohistochemistry
Purity
IGF-1R antibody was purified by immunoaffinity chromatography.
Synonyms
IGF-1R, Antibody; IGF-1R antibody; Polyclonal IGF-1R; Anti-IGF-1R; IGF-R 1; IGF-R-1; Insulin-like Growth Factor 1 Receptor; IGF 1; Ab 1280; IGF-1R; IGF-1; anti-IGF-1R antibody
Host
Rabbit
Clonality
Polyclonal
Purity/Purification
IGF-1R antibody was purified by immunoaffinity chromatography.
Form/Format
Supplied in liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
1369
Applicable Applications for anti-IGF-1R antibody
WB (Western Blot), IHC (Immunohistochemistry)
Biological Significance
IGF-1R is a transmembrane receptor that is activated by IGF-1 and by the related growth factor IGF-2. It belongs to the large class of tyrosine kinase receptors. This receptor mediates the effects of IGF-1, which is a polypeptide protein hormone similar in molecular structure to insulin. IGF-1 plays an important role in growth and continues to have anabolic effects in adults - meaning that it can induce hypertrophy of skeletal muscle and other target tissues. Mice lacking the IGF-1 receptor die late in development, and show a dramatic reduction in body mass, testifying to the strong growth-promoting effect of this receptor.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
IGF-1R antibody was raised in Rabbit using the peptide sequence around aa 1278~1282 (S-F-Y-Y-S) derived from Human IGF-1R as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
WB (Western Blot)
(Western Blot analysis of extracts from 293,3T3 and Hela cells using IGF-1R antibody)
WB (Western Blot)
(Western Blot analysis of extracts from 293,3T3 and Hela cells using IGF-1R antibody)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IGF-1R antibody (left) or the same antibody preincubated with with blocking peptide (right))
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IGF-1R antibody (left) or the same antibody preincubated with with blocking peptide (right))
Related Product Information for anti-IGF-1R antibody
Rabbit polyclonal IGF-1R antibody
Product Categories/Family for anti-IGF-1R antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
155,788 Da
NCBI Official Full Name
insulin-like growth factor 1 receptor
NCBI Official Synonym Full Names
insulin-like growth factor I receptor
NCBI Official Symbol
Igf1r
NCBI Official Synonym Symbols
hyft; CD221; IGF-1R; D930020L01; A330103N21Rik
NCBI Protein Information
insulin-like growth factor 1 receptor
UniProt Protein Name
Insulin-like growth factor 1 receptor
UniProt Gene Name
Igf1r
UniProt Synonym Gene Names
IGF-I receptor
UniProt Entry Name
IGF1R_MOUSE
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Product Notes
The IGF-1R igf1r (Catalog #AAA107869) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IGF-1R can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the IGF-1R igf1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGF-1R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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