Rabbit IGF2BP1 Polyclonal Antibody | anti-IGF2BP1 antibody

IGF2BP1 Antibody (C-term)

Cat. Num. AAA284762

• Gene Names: IGF2BP1; IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1
• Reactivity: Human (Predicted Reactivity: Xenopus, Mouse, Rat, Chicken, Zebrafish)
• Applications: Flow Cytometry, Functional Assay, Immunohistochemistry, ELISA, Western Blot
• Purity: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Synonyms: IGF2BP1, Antibody; IGF2BP1 Antibody (C-term); Insulin-like growth factor 2 mRNA-binding protein 1; IGF2 mRNA-binding protein 1; IMP-1; IMP1; Coding region determinant-binding protein; CRD-BP; IGF-II mRNA-binding protein 1; VICKZ family member 1; Zipcode-binding protein 1; ZBP-1; IGF2BP1; CRDBP; VICKZ1; ZBP1; anti-IGF2BP1 antibody

• Host: Rabbit
• Reactivity: Human (Predicted Reactivity: Xenopus, Mouse, Rat, Chicken, Zebrafish)
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This IGF2BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-534 amino acids from the C-terminal region of human IGF2BP1.
• Purity/Purification: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Vial Concentration: 0.5 (varies by lot)
• Sequence Positions: 508-534
• Sequence Length: 438

• Applicable Applications for anti-IGF2BP1 antibody: FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot)
• Antigen Type: Synthetic Peptide
• Antigen Source: HUMAN
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

FCM/FACS (Flow Cytometry)

(IGF2BP1 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

IHC (Immunohiostchemistry)

(IGF2BP1 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IGF2BP1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

WB (Western Blot)

(IGF2BP1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the IGF2BP1 antibody detected the IGF2BP1 protein (arrow).)

Related Product Information for anti-IGF2BP1 antibody

IGF2BP1 is a member of the insulin-like growth
factor 2 mRNA-binding protein family. The protein encoded by this
gene contains four K homology domains and two RNA recognition
motifs. It functions by binding to the mRNAs of certain genes,
including insulin-like growth factor 2, beta-actin and
beta-transducin repeat-containing protein, and regulating their
translation. Two transcript variants encoding different isoforms
have been found for this gene.

References

Rodriguez, S., et al. Growth Horm. IGF Res. 20(4):310-318(2010)
Pillas, D., et al. PLoS Genet. 6 (2), E1000856 (2010) :
Noubissi, F.K., et al. Cancer Res. 69(22):8572-8578(2009)
Zhou, Y., et al. Virology 393(2):210-220(2009)
Kawakami, Y., et al. Biosci. Biotechnol. Biochem. 73(8):1811-1817(2009)

NCBI and Uniprot Product Information

• NCBI GI #: 238624257
• NCBI GeneID: 10642
• NCBI Accession #: NP_001153895.1; NP_006537.3
• NCBI GenBank Nucleotide #: NM_001160423.1
• UniProt Accession #: Q9NZI8; C9JT33
• Molecular Weight: 63481
• NCBI Official Full Name: insulin-like growth factor 2 mRNA-binding protein 1 isoform 2
• NCBI Official Synonym Full Names: insulin-like growth factor 2 mRNA binding protein 1
• NCBI Official Symbol: IGF2BP1
• NCBI Official Synonym Symbols: IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1
• NCBI Protein Information: insulin-like growth factor 2 mRNA-binding protein 1
• UniProt Protein Name: Insulin-like growth factor 2 mRNA-binding protein 1
• UniProt Gene Name: IGF2BP1
• UniProt Synonym Gene Names: CRDBP; VICKZ1; ZBP1; IGF2 mRNA-binding protein 1; IMP-1; IMP1; CRD-BP; ZBP-1
• UniProt Entry Name: IF2B1_HUMAN