IF (Immunofluorescence)
(IF of IgM on a FFPE Colon Tissue)
Rabbit IgM Polyclonal Antibody | anti-IgM antibody
IgM/FITC, Rpab
Applications
Immunohistochemistry
Synonyms
IgM, Antibody; IgM/FITC, Rpab; anti-IgM antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Form/Format
Concentrate or Prediluted
Sequence Length
112
Applicable Applications for anti-IgM antibody
IHC (Immunohistochemistry)
Immunogen
Purified human IgM heavy chain.
Localization
Cytoplasmic
Control
Tonsil, Lymph Node, Spleen, Kidney, Colon
Preparation and Storage
Store at 2-8 degree C in the dark.
IF (Immunofluorescence)
(IF of IgM on a FFPE Colon Tissue)
IF (Immunofluorescence)
(IF of IgM on a FFPE Colon Tissue)
Dilution Info
Dilution Info
Related Product Information for anti-IgM antibody
IgM forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, normally as a pentamer or occasionally as a hexamer. It has a large molecular mass of approximately 900 kDa (in its pentamer form). In germline cells, the gene segment encoding the constant region of the heavy chain is positioned first among other constant region gene segments. For this reason, IgM is the first immunoglobulin expressed by mature B-cells.
IgM antibody reacts with surface immunoglobulin IgM mu chains. IgM is one of the predominant surface immunoglobulins on B-lymphocytes, and is useful when identifying Leukemias, Plasmacytomas, and B-cell lineage derived Hodgkin’s Lymphomas. Due to the restricted expression of heavy and light chains in these diseases, demonstration of B-cell Lymphomas is possible with clonal generearrangement studies. Lupus nephritis is an inflammation of the kidneys caused by Systemic Lupus Erythematosus. Immunofluorescence reveals positively for IgG, IgA, IgM, C3, and C1q. Clinically, hematuria and proteinuria are present, with or without nephrotic syndromes. Immunoglobulin M (IgM) nephropathy is an uncommon glomerular disease characterized by IgM deposits in the mesangium.
IgM antibody reacts with surface immunoglobulin IgM mu chains. IgM is one of the predominant surface immunoglobulins on B-lymphocytes, and is useful when identifying Leukemias, Plasmacytomas, and B-cell lineage derived Hodgkin’s Lymphomas. Due to the restricted expression of heavy and light chains in these diseases, demonstration of B-cell Lymphomas is possible with clonal generearrangement studies. Lupus nephritis is an inflammation of the kidneys caused by Systemic Lupus Erythematosus. Immunofluorescence reveals positively for IgG, IgA, IgM, C3, and C1q. Clinically, hematuria and proteinuria are present, with or without nephrotic syndromes. Immunoglobulin M (IgM) nephropathy is an uncommon glomerular disease characterized by IgM deposits in the mesangium.
Product Categories/Family for anti-IgM antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
IgM, partial
Similar Products
Product Notes
The IgM (Catalog #AAA59328) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IgM can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the IgM for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IgM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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