IHC (Immunohiostchemistry)
(Immunohistochemistry of IKK epsilon in human pancreas tissue with IKK epsilon antibody at 10 ug/mL.)
Rabbit anti-Human IKK epsilon Polyclonal Antibody | anti-IKK epsilon antibody
IKK epsilon Antibody
Gene Names
IKBKE; IKKE; IKKI; IKK-E; IKK-i
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
IKK epsilon, Antibody; IKK epsilon Antibody; IKKi, IKKe; anti-IKK epsilon antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
It has no cross response to IKKa, IKKb, or IKKy.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
2151
Applicable Applications for anti-IKK epsilon antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a peptide corresponding to amino acids 701 to 716 of human IKK epsilon/IKK-i.
Target Name
IKK epsilon
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of IKK epsilon in human pancreas tissue with IKK epsilon antibody at 10 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of IKK epsilon in human pancreas tissue with IKK epsilon antibody at 10 ug/mL.)
WB (Western Blot)
(Western blot analysis of IKK epsilon in Jurkat whole cell lysate with IKK epsilon/IKK-i antibody at 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of IKK epsilon in Jurkat whole cell lysate with IKK epsilon/IKK-i antibody at 1 ug/mL.)
Related Product Information for anti-IKK epsilon antibody
Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. IkB is phosphorylated by IkB kinase (IKK) complex that contains IKKa, IKKb, and IKKg. A novel molecule in the IKK complex was recently identified and designated IKKeta/IKK-i. IKK epsilon is required for the activation of NF-kB by PMA and T cell receptors but not by TNFa and IL-1. IKKeta/IKK-i message is expressed in a variety of tissues and is inducible by TNFa, IL-1, and LPS.
Product Categories/Family for anti-IKK epsilon antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
70,816 Da
NCBI Official Full Name
Homo sapiens IKK epsilon mRNA, complete cds
NCBI Official Synonym Full Names
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
NCBI Official Symbol
IKBKE
NCBI Official Synonym Symbols
IKKE; IKKI; IKK-E; IKK-i
NCBI Protein Information
inhibitor of nuclear factor kappa-B kinase subunit epsilon
UniProt Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
UniProt Gene Name
IKBKE
UniProt Synonym Gene Names
IKKE; IKKI; KIAA0151; I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IkBKE; IKK-i
UniProt Entry Name
IKKE_HUMAN
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Product Notes
The IKK epsilon ikbke (Catalog #AAA303326) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IKK epsilon Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IKK epsilon can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the IKK epsilon ikbke for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IKK epsilon, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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