Rabbit anti-Human, Mouse IL-23 Polyclonal Antibody | anti-IL23A antibody

IL-23 Antibody

Cat. Num. AAA40296

• Gene Names: IL23A; P19; SGRF; IL-23; IL-23A; IL23P19
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: IL-23 Antibody is affinity chromatography purified via peptide column.
• Synonyms: IL-23, Antibody; IL-23 Antibody; IL-23; P19; SGRF; IL-23A; IL23P19; UNQ2498/PRO5798; Interleukin-23 subunit alpha; Interleukin-23 subunit p19; IL-23 subunit alpha; interleukin 23, alpha subunit p19; anti-IL23A antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: IL-23 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 189

• Applicable Applications for anti-IL23A antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: IL-23 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human IL-23.
• Buffer: IL-23 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: IL-23 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of IL-23 in human pancreas tissue with IL-23 antibody at 20 μg/ml.Red: IL-23 Antibody (3793)Blue: DAPI staining)

ICC (Immunocytochemistry)

(Immunocytochemistry of IL-23 in Raji cells with IL-23 antibody at 10 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of IL-23 in Raji cells with IL-23 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of IL-23 in human pancreas tissue with IL-23 antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of IL-23 in Raji lysate with IL-23 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.)

Related Product Information for anti-IL23A antibody

IL-23 Antibody: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-α from activated T cells, and can stimulate macrophages to produce TNF-α and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.

NCBI and Uniprot Product Information

• NCBI GI #: 42542809
• NCBI GeneID: 51561
• UniProt Accession #: Q9NPF7; Q6NZ80; Q6NZ82; Q9H2A5
• Molecular Weight: 21 kDa
• NCBI Official Full Name: Interleukin 23, alpha subunit p19
• NCBI Official Synonym Full Names: interleukin 23, alpha subunit p19
• NCBI Official Symbol: IL23A
• NCBI Official Synonym Symbols: P19; SGRF; IL-23; IL-23A; IL23P19
• NCBI Protein Information: interleukin-23 subunit alpha; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin 23 p19 subunit; interleukin-23 subunit p19; JKA3 induced upon T-cell activation; interleukin-six, G-CSF related factor
• UniProt Protein Name: Interleukin-23 subunit alpha
• UniProt Gene Name: IL23A
• UniProt Synonym Gene Names: SGRF; IL-23 subunit alpha; IL-23-A; IL-23p19
• UniProt Entry Name: IL23A_HUMAN