Rabbit anti-Human IL2 Polyclonal Antibody | anti-IL2 antibody

IL2 Antibody

Cat. Num. AAA301932

• Gene Names: IL2; IL-2; TCGF; lymphokine
• Reactivity: Human
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: IL2, Antibody; IL2 Antibody; IL2; IL-2; TCGF; lymphokine; anti-IL2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total IL2 protein.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 153

• Applicable Applications for anti-IL2 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human IL2.
• Target Name: IL2
• Preparation and Storage: Store at -20 degree C

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human esophageal cancer using IL-2 antibody at dilution of 1:100 (200x lens).)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human liver cancer using IL-2 antibody at dilution of 1:100 (200x lens).)

IHC (Immunohistochemisry)

(Immunohistochemical analysis of paraffin-embedded mouse spleen using IL-2 antibody at dilution of 1:100 (400x lens).)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded mouse spleen using IL-2 antibody at dilution of 1:100 (200x lens).)

WB (Western Blot)

(Western blot analysis of CTLL-2 cell lysate using IL-2 antibody.)

Related Product Information for anti-IL2 antibody

IL-2 is a T cell stimulatory cytokine best known for inducing T cell proliferation and NK cell proliferation and activation (1,2). IL-2 also promotes peripheral development of Treg cells (4, 5). Conversely, IL-2 is involved in activation induced cell death (AICD) that is observed post T cell expansion by increasing levels of Fas on CD4+ T cells (3). The effects of IL-2 are mediated through a trimeric receptor complex consisting of IL-2Ra, IL-2Rb and the common gamma chain, gc (1,2). IL-2 Ra binds exclusively to IL-2 with low affinity and increases binding affinity of the whole receptor complex including IL-2Rb and gc subunits. IL-2Rb is also used by IL-15 (1,2). The common gc is used by other cytokines including IL-4, IL-7, IL-9, IL-15, and IL-21 (1,2). Binding of IL-2 initiates signaling cascades involving Jak1, Jak3, Stat5 and the PI3K/Akt pathways (1,2).

Product Categories/Family for anti-IL2 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 28178861
• NCBI GeneID: 3558
• NCBI Accession #: NP_000577.2
• NCBI GenBank Nucleotide #: NM_000586.3
• UniProt Accession #: P60568; P01585
• Molecular Weight: 17,628 Da
• NCBI Official Full Name: interleukin-2
• NCBI Official Synonym Full Names: interleukin 2
• NCBI Official Symbol: IL2
• NCBI Official Synonym Symbols: IL-2; TCGF; lymphokine
• NCBI Protein Information: interleukin-2
• UniProt Protein Name: Interleukin-2
• UniProt Gene Name: IL2
• UniProt Synonym Gene Names: IL-2; TCGF
• UniProt Entry Name: IL2_HUMAN