WB (Western Blot)
(Western blot analysis of lysates from A549, Hela, MCF-7, SH-SY5Y, SW480 cell line (from left to right), using INSRR Antibody (Center). AAA287433 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Rabbit anti-Human INSRR Polyclonal Antibody | anti-INSRR antibody
INSRR Antibody (Center)
Gene Names
INSRR; IRR
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
INSRR, Antibody; INSRR Antibody (Center); Insulin receptor-related protein; IRR; IR-related receptor; Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain; INSRR; anti-INSRR antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This INSRR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 668-702 amino acids from the Central region of human INSRR.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
1,297
Applicable Applications for anti-INSRR antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Crown Antibody
Yes
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of lysates from A549, Hela, MCF-7, SH-SY5Y, SW480 cell line (from left to right), using INSRR Antibody (Center). AAA287433 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
WB (Western Blot)
(Western blot analysis of lysates from A549, Hela, MCF-7, SH-SY5Y, SW480 cell line (from left to right), using INSRR Antibody (Center). AAA287433 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded H. kidney section using INSRR Antibody (Center). AAA287433 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded H. kidney section using INSRR Antibody (Center). AAA287433 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded H. breast carcinoma section using INSRR Antibody (Center). AAA287433 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded H. breast carcinoma section using INSRR Antibody (Center). AAA287433 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.)
Related Product Information for anti-INSRR antibody
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Product Categories/Family for anti-INSRR antibody
References
Haenze J.,et al.Horm. Metab. Res. 31:77-79(1999).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Shier P.,et al.J. Biol. Chem. 264:14605-14608(1989).
Greenman C.,et al.Nature 446:153-158(2007).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Shier P.,et al.J. Biol. Chem. 264:14605-14608(1989).
Greenman C.,et al.Nature 446:153-158(2007).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
143720
NCBI Official Full Name
insulin receptor-related protein
NCBI Official Synonym Full Names
insulin receptor-related receptor
NCBI Official Symbol
INSRR
NCBI Official Synonym Symbols
IRR
NCBI Protein Information
insulin receptor-related protein
UniProt Protein Name
Insulin receptor-related protein
UniProt Gene Name
INSRR
UniProt Synonym Gene Names
IRR; IRR
UniProt Entry Name
INSRR_HUMAN
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Product Notes
The INSRR insrr (Catalog #AAA287433) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The INSRR Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's INSRR can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the INSRR insrr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "INSRR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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