Rabbit anti-Human IPAF / NLRC4 Polyclonal Antibody | anti-IPAF antibody

Rabbit Polyclonal to Human IPAF / NLRC4

Cat. Num. AAA50724

• Gene Names: NLRC4; CLAN; IPAF; AIFEC; CLAN1; CLANA; CLANB; CLANC; CLAND; FCAS4; CARD12; CLR2.1
• Reactivity: Human
• Applications: Western Blot, Immunocytochemistry, Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: IPAF / NLRC4, Antibody; Rabbit Polyclonal to Human IPAF / NLRC4; Anti-IPAF / NLRC4 Antibody (C-Terminus) IHC-plus; NLRC4; CARD12; CLANA; CLANB; CLANC; CLAND; CLAN; CLR2.1; Clan protein; CLAN1; Ice protease-activating factor; NOD-like receptor C4; ICE-protease activating factor; IPAF; Human IPAF; anti-IPAF antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: synthetic peptide corresponding to amino acids near the C-terminus of human Ipaf
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.02% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 1024

• Applicable Applications for anti-IPAF antibody: WB (Western Blot), ICC (Immunocytochemistry), IHC (Immunohistochemistry)
• Target Species: Human
• Immunogen Description: Synthetic peptide from human NLRC4 / IPAF.
• Immunogen Type: Synthetic peptide
• Immunogen: IPAF / NLRC4 antibody was raised against synthetic peptide from human NLRC4 / IPAF.
• Antigen Modification: C-Terminus
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

WB (Western Blot)

(Western blot of Ipaf in human PBL lysate with Ipaf antibody at 0.5 (lane A), 1 (lane B), and 2 (lane C) ug/ml, respectively.)

ICC (Immunocytochemistry)

(Immunocytochemistry of Ipaf in THP-1 cells with Ipaf antibody at 10 ug/ml.)

IF (Immunofluorescence)

(Immunofluorescence of Ipaf in THP1 cells with Ipaf antibody at 10 ug/ml.)

IHC (Immunohistochemistry)

(Anti-NLRC4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Related Product Information for anti-IPAF antibody

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adaptor molecules and proteases including several members of the caspase family. Another family of proteins that functions as a critical regulator of apoptosis and NF-kB signaling pathways is the CED-4/Apaf-1 (apoptosis protein activating factor-1) protein family.

Product Categories/Family for anti-IPAF antibody

Family: Apoptosis

NCBI and Uniprot Product Information

• NCBI GI #: 40788015
• NCBI GeneID: 58484
• NCBI Accession #: NP_067032.3
• NCBI GenBank Nucleotide #: NM_021209.4
• UniProt Accession #: Q9NPP4; Q96J81; Q96J82; Q96J83; A8K9F8; B2RBQ3; B3KTF0; D6W580
• Molecular Weight: 10,646 Da
• NCBI Official Full Name: NLR family CARD domain-containing protein 4 isoform a
• NCBI Official Synonym Full Names: NLR family, CARD domain containing 4
• NCBI Official Symbol: NLRC4
• NCBI Official Synonym Symbols: CLAN; IPAF; AIFEC; CLAN1; CLANA; CLANB; CLANC; CLAND; FCAS4; CARD12; CLR2.1
• NCBI Protein Information: NLR family CARD domain-containing protein 4; NOD-like receptor C4; ICE-protease activating factor; CARD, LRR, and NACHT-containing protein; caspase recruitment domain family, member 12; caspase recruitment domain-containing protein 12; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4
• UniProt Protein Name: NLR family CARD domain-containing protein 4
• UniProt Gene Name: NLRC4
• UniProt Synonym Gene Names: CARD12; CLAN; CLAN1; IPAF; Clan protein; Ipaf
• UniProt Entry Name: NLRC4_HUMAN