IHC (Immunohiostchemistry)
(Immunohistochemical staining of rat liver cells using IRAK-M antibody at 2 ug/mL.)
Rabbit IRAK-M Polyclonal Antibody | anti-IRAK-M antibody
IRAK-M Antibody
Gene Names
IRAK3; ASRT5; IRAKM
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
IRAK-M, Antibody; IRAK-M Antibody; anti-IRAK-M antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
IRAK-M antibody has no cross response to IRAK or IRAK2.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
2288
Applicable Applications for anti-IRAK-M antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a peptide corresponding to amino acids from the carboxy terminus of human IRAK-M.
Target Name
IRAK-M
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemical staining of rat liver cells using IRAK-M antibody at 2 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemical staining of rat liver cells using IRAK-M antibody at 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of IRAK-M in mouse spleen (M) and rat liver (R) tissue lysates with IRAK-M antibody at 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of IRAK-M in mouse spleen (M) and rat liver (R) tissue lysates with IRAK-M antibody at 1 ug/mL.)
Related Product Information for anti-IRAK-M antibody
Interleukin-1 (IL-1) and lipopolysaccharide (LPS) induces cellular response through IL-1 receptor (IL-1R) and Toll like receptors (TLR). IL-1 receptor-associated kinase (IRAK and IRAK2) mediates the activation of NF-betaB by IL-1/Toll receptors, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK-M. IRAKs associate with IL-1/Toll receptors after IL-1 or LPS stimulation and the dominant negative mutants of IRAKs inhibit IL-1 or LPS induced NF-betaB activation. Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses to cytokine IL-1 and LPS.
Product Categories/Family for anti-IRAK-M antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
60,608 Da
NCBI Official Full Name
Homo sapiens IL-1 receptor-associated-kinase-M mRNA, complete cds
NCBI Official Synonym Full Names
interleukin-1 receptor-associated kinase 3
NCBI Official Symbol
IRAK3
NCBI Official Synonym Symbols
ASRT5; IRAKM
NCBI Protein Information
interleukin-1 receptor-associated kinase 3
UniProt Protein Name
Interleukin-1 receptor-associated kinase 3
UniProt Gene Name
IRAK3
UniProt Synonym Gene Names
IRAK-3; IRAK-M
UniProt Entry Name
IRAK3_HUMAN
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Product Notes
The IRAK-M irak3 (Catalog #AAA304389) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IRAK-M Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IRAK-M can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the IRAK-M irak3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IRAK-M, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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