IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human endometrial cancer using AAA231320 at dilution 1:100)
Rabbit anti-Human ISCU Polyclonal Antibody | anti-ISCU antibody
ISCU Antibody
Gene Names
ISCU; HML; ISU2; NIFU; NIFUN; hnifU; 2310020H20Rik
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purified
Synonyms
ISCU, Antibody; ISCU Antibody; Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; NifU-like N-terminal domain-containing protein; NifU-like protein; ISCU; NIFUN; anti-ISCU antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
154
Applicable Applications for anti-ISCU antibody
IHC (Immunohistochemistry), ELISA
Species
Human
Immunogen
Recombinant human Iron-sulfur cluster assembly enzyme ISCU, mitochondrial protein (1-167AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-16784 / sc-31743 / sc-31744 / sc-28860
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human endometrial cancer using AAA231320 at dilution 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human endometrial cancer using AAA231320 at dilution 1:100)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human lung cancer using AAA231320 at dilution 1:100)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human lung cancer using AAA231320 at dilution 1:100)
Related Product Information for anti-ISCU antibody
Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (PubMed:11060020). First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU. In a second step, the cluster is released from ISCU, transferred to a glutaredoxin GLRX5, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISCU depends on the function of the cysteine desulfurase complex NFS1-LYRM4/ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15,263 Da
NCBI Official Full Name
iron-sulfur cluster assembly enzyme ISCU, mitochondrial isoform 3
NCBI Official Synonym Full Names
iron-sulfur cluster assembly enzyme
NCBI Official Symbol
ISCU
NCBI Official Synonym Symbols
HML; ISU2; NIFU; NIFUN; hnifU; 2310020H20Rik
NCBI Protein Information
iron-sulfur cluster assembly enzyme ISCU, mitochondrial
UniProt Protein Name
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial
UniProt Gene Name
ISCU
UniProt Synonym Gene Names
NIFUN
UniProt Entry Name
ISCU_HUMAN
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Product Notes
The ISCU iscu (Catalog #AAA231320) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ISCU Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ISCU can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the ISCU iscu for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ISCU, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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