WB (Western Blot)
(ISCU Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ISCU antibody detected the ISCU protein (arrow).)
Rabbit anti-Human, mouse ISCU Polyclonal Antibody | anti-ISCU antibody
ISCU Antibody (C-term)
Gene Names
ISCU; HML; ISU2; NIFU; NIFUN; hnifU; 2310020H20Rik
Reactivity
Human, mouse
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ISCU, Antibody; ISCU Antibody (C-term); Iron-sulfur cluster assembly enzyme ISCU; mitochondrial; NifU-like N-terminal domain-containing protein; NifU-like protein; ISCU; NIFUN; anti-ISCU antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ISCU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the C-terminal region of human ISCU.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.29 (varies by lot)
Sequence Positions
138-167
Sequence Length
142
Applicable Applications for anti-ISCU antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(ISCU Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ISCU antibody detected the ISCU protein (arrow).)
WB (Western Blot)
(ISCU Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ISCU antibody detected the ISCU protein (arrow).)
WB (Western Blot)
(ISCU Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the ISCU antibody detected the ISCU protein (arrow).)
WB (Western Blot)
(ISCU Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the ISCU antibody detected the ISCU protein (arrow).)
Related Product Information for anti-ISCU antibody
Iron-sulfur (Fe-S) clusters are necessary for several
mitochondrial enzymes and other subcellular compartment proteins.
They contain sulfur and iron, and are created via several steps
that include cysteine desulfurases, iron donors, chaperones, and
scaffold proteins. This gene encodes the two isomeric forms, ISCU1
and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this
gene have been found in patients with myopathy with severe exercise
intolerance and myoglobinuria.
mitochondrial enzymes and other subcellular compartment proteins.
They contain sulfur and iron, and are created via several steps
that include cysteine desulfurases, iron donors, chaperones, and
scaffold proteins. This gene encodes the two isomeric forms, ISCU1
and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this
gene have been found in patients with myopathy with severe exercise
intolerance and myoglobinuria.
Product Categories/Family for anti-ISCU antibody
References
Chen, Z., et al. Oncogene 29(30):4362-4368(2010)
Chan, S.Y., et al. Cell Metab. 10(4):273-284(2009)
Kollberg, G., et al. Brain 132 (PT 8), 2170-2179 (2009) :
Huang, J., et al. J. Biol. Inorg. Chem. 13(5):825-836(2008)
Mochel, F., et al. Am. J. Hum. Genet. 82(3):652-660(2008)
Chan, S.Y., et al. Cell Metab. 10(4):273-284(2009)
Kollberg, G., et al. Brain 132 (PT 8), 2170-2179 (2009) :
Huang, J., et al. J. Biol. Inorg. Chem. 13(5):825-836(2008)
Mochel, F., et al. Am. J. Hum. Genet. 82(3):652-660(2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17999
NCBI Official Full Name
iron-sulfur cluster assembly enzyme ISCU, mitochondrial isoform ISCU1
NCBI Official Synonym Full Names
iron-sulfur cluster assembly enzyme
NCBI Official Symbol
ISCU
NCBI Official Synonym Symbols
HML; ISU2; NIFU; NIFUN; hnifU; 2310020H20Rik
NCBI Protein Information
iron-sulfur cluster assembly enzyme ISCU, mitochondrial
UniProt Protein Name
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial
UniProt Gene Name
ISCU
UniProt Synonym Gene Names
NIFUN
UniProt Entry Name
ISCU_HUMAN
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Product Notes
The ISCU iscu (Catalog #AAA287704) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 138-167. The ISCU Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ISCU can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the ISCU iscu for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ISCU, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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