IHC (Immunohistochemisry)
(ITGAX/CD11c Antibody-Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit ITGAX/CD11c Polyclonal Antibody | anti-ITGAX antibody
ITGAX/CD11c Rabbit anti-Mouse Polyclonal Antibody
Gene Names
ITGAX; CD11C; SLEB6
Reactivity
Mouse, Rat, Human
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Affinity purification
Synonyms
ITGAX/CD11c, Antibody; ITGAX/CD11c Rabbit anti-Mouse Polyclonal Antibody; PathPlus ITGAX/CD11c Antibody; ITGAX; CD11c antigen; Integrin alpha-X; Leu M5; alpha subunit; p150 95 integrin alpha chain; SLEB6; CD11C; anti-ITGAX antibody
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS, pH7.4, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
Concentration
0.98mg/ml (varies by lot)
Applicable Applications for anti-ITGAX antibody
WB (Western Blot), IHC (Immunohistochemistry), IF (Immunofluorescence)
Target
Mouse ITGAX/CD11c
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse CD11c
Conjugation
Unconjugated
Family
Integrin
Preparation and Storage
Store at -20 degree C. Avoid freeze-thaw cycles.
IHC (Immunohistochemisry)
(ITGAX/CD11c Antibody-Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemisry)
(ITGAX/CD11c Antibody-Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(ITGAX/CD11c Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(ITGAX/CD11c Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(ITGAX/CD11c Antibody-Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(ITGAX/CD11c Antibody-Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-ITGAX antibody
CD11c antibody is an unconjugated rabbit polyclonal antibody to CD11c (ITGAX) from mouse. It is reactive with human, mouse and rat. Validated for IF, IHC and WB.
ITGAX (CD11c) is the integrin alpha X chain protein that functions as a fibrinogen receptor. ITGAX plays a role in monocyte adhesion and chemotaxis, and can induce cellular activation and trigger neutrophil respiratory burst. In cancer, it is positive in leukemia, including the hairy cell, acute nonlymphocytic and B-cell chronic lymphocytic subtypes, and follicular and lymphoplasmacytic lymphoma. In obesity, CD206 and TGAX/CD11c positive macrophages in adipose tissue are correlated with insulin resistance. In immunohistochemistry, ITGAX is found on dendritic cells, monocytes, granulocytes, macrophages, neutrophils, some B cells, as well as roughly half of activated CD4 and CD8 positive T cells. It is commonly used to identify histiocytes and NK cells, and also in the identification of leukemia.
ITGAX (CD11c) is the integrin alpha X chain protein that functions as a fibrinogen receptor. ITGAX plays a role in monocyte adhesion and chemotaxis, and can induce cellular activation and trigger neutrophil respiratory burst. In cancer, it is positive in leukemia, including the hairy cell, acute nonlymphocytic and B-cell chronic lymphocytic subtypes, and follicular and lymphoplasmacytic lymphoma. In obesity, CD206 and TGAX/CD11c positive macrophages in adipose tissue are correlated with insulin resistance. In immunohistochemistry, ITGAX is found on dendritic cells, monocytes, granulocytes, macrophages, neutrophils, some B cells, as well as roughly half of activated CD4 and CD8 positive T cells. It is commonly used to identify histiocytes and NK cells, and also in the identification of leukemia.
References
The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; Diabetes 2010;59:1648, PMID: 20357360; McKusick, Hamosh. Online Mendelian Inheritance in Man, OMIM. Johns Hopkins University, Baltimore, MD. MIM Number: 151510, URL: https://omim.org/ OMIM: 151510; Am J Clin Pathol 2005;124:414, PMID: 16191510; Am J Clin Pathol 1998;110:582, PMID: 9802342;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
150kDa
NCBI Official Full Name
integrin alpha-X
NCBI Official Synonym Full Names
integrin, alpha X (complement component 3 receptor 4 subunit)
NCBI Official Symbol
ITGAX
NCBI Official Synonym Symbols
CD11C; SLEB6
NCBI Protein Information
integrin alpha-X; leu M5, alpha subunit; p150 95 integrin alpha chain; CD11 antigen-like family member C; leukocyte adhesion receptor p150,95; myeloid membrane antigen, alpha subunit; leukocyte surface antigen p150,95, alpha subunit; leukocyte adhesion gl
UniProt Protein Name
Integrin alpha-X
UniProt Gene Name
ITGAX
UniProt Synonym Gene Names
CD11C
UniProt Entry Name
ITAX_HUMAN
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Product Notes
The ITGAX itgax (Catalog #AAA163067) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ITGAX/CD11c Rabbit anti-Mouse Polyclonal Antibody reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's ITGAX/CD11c can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IF (Immunofluorescence). Researchers should empirically determine the suitability of the ITGAX itgax for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ITGAX/CD11c, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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