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product-image-AAA232548_IF10.jpg IF (Immunofluorescence) (Immunofluorescent analysis of A549 cells using AAA232548 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Rabbit anti-Human, Mouse ITGB4 Polyclonal Antibody | anti-ITGB4 antibody

ITGB4 Antibody

Gene Names
ITGB4; CD104; GP150
Reactivity
Human, Mouse
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
>95%, Protein G purified
Synonyms
ITGB4, Antibody; ITGB4 Antibody; Integrin beta-4; GP150; CD104; ITGB4; anti-ITGB4 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
1822
Applicable Applications for anti-ITGB4 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Recombinant Human Integrin beta-4 protein (1401-1533AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-55514 / sc-55514 / sc-6629
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

IF (Immunofluorescence)

(Immunofluorescent analysis of A549 cells using AAA232548 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

product-image-AAA232548_IF10.jpg IF (Immunofluorescence) (Immunofluorescent analysis of A549 cells using AAA232548 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded human pancreatic cancer using AAA232548 at dilution of 1:100)

product-image-AAA232548_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded human pancreatic cancer using AAA232548 at dilution of 1:100)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human placenta tissue using AAA232548 at dilution of 1:100)

product-image-AAA232548_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human placenta tissue using AAA232548 at dilution of 1:100)

WB (Western Blot)

(Western BlotPositive WB detected in:Mouse brain tissueAll lanes: ITGB4 antibody at 3.5ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 203,196,201,195,107 kDaObserved band size: 203 kDa)

product-image-AAA232548_WB15.jpg WB (Western Blot) (Western BlotPositive WB detected in:Mouse brain tissueAll lanes: ITGB4 antibody at 3.5ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 203,196,201,195,107 kDaObserved band size: 203 kDa)
Related Product Information for anti-ITGB4 antibody
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6: ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed: 20682778). ITGA6: ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed: 22351760).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
106,779 Da
NCBI Official Full Name
integrin beta-4 isoform 1
NCBI Official Synonym Full Names
integrin subunit beta 4
NCBI Official Symbol
ITGB4
NCBI Official Synonym Symbols
CD104; GP150
NCBI Protein Information
integrin beta-4
UniProt Protein Name
Integrin beta-4
UniProt Gene Name
ITGB4
UniProt Entry Name
ITB4_HUMAN

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Product Notes

The ITGB4 itgb4 (Catalog #AAA232548) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ITGB4 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ITGB4 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ITGB4 itgb4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ITGB4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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