IHC (Immunohiostchemistry)
(JHDM2a Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of JHDM2a Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human, mouse JHDM2a Polyclonal Antibody | anti-KDM3A antibody
JHDM2a Antibody (N-term)
Gene Names
KDM3A; TSGA; JMJD1; JHDM2A; JHMD2A; JMJD1A
Reactivity
Human, mouse
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
JHDM2a, Antibody; JHDM2a Antibody (N-term); Lysine-specific demethylase 3A; 11411-; JmjC domain-containing histone demethylation protein 2A; Jumonji domain-containing protein 1A; KDM3A; JHDM2A; JMJD1; JMJD1A; KIAA0742; TSGA; anti-KDM3A antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This JHDM2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human JHDM2a.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
50-79
Sequence Length
1,321
Applicable Applications for anti-KDM3A antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(JHDM2a Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of JHDM2a Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(JHDM2a Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of JHDM2a Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(JHDM2a Antibody (N-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the JHDM2a antibody detected the JHDM2a protein (arrow).)
WB (Western Blot)
(JHDM2a Antibody (N-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the JHDM2a antibody detected the JHDM2a protein (arrow).)
Related Product Information for anti-KDM3A antibody
JHDM2a is a zinc finger protein that contains a jumonji domain. It is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. This protein preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. It is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation.
References
Wellmann,S., Biochem. Biophys. Res. Commun. 372 (4), 892-897 (2008)
Yamane,K., Cell 125 (3), 483-495 (2006)
Yamane,K., Cell 125 (3), 483-495 (2006)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
147341
NCBI Official Full Name
lysine-specific demethylase 3A
NCBI Official Synonym Full Names
lysine (K)-specific demethylase 3A
NCBI Official Symbol
KDM3A
NCBI Official Synonym Symbols
TSGA; JMJD1; JHDM2A; JHMD2A; JMJD1A
NCBI Protein Information
lysine-specific demethylase 3A
UniProt Protein Name
Lysine-specific demethylase 3A
UniProt Gene Name
KDM3A
UniProt Synonym Gene Names
JHDM2A; JMJD1; JMJD1A; KIAA0742; TSGA
UniProt Entry Name
KDM3A_HUMAN
Similar Products
Product Notes
The KDM3A kdm3a (Catalog #AAA288369) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 50-79. The JHDM2a Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's JHDM2a can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the KDM3A kdm3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JHDM2a, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.