Rabbit JMJD1A Polyclonal Antibody | anti-KDM3A antibody

JMJD1A Antibody

Cat. Num. AAA40238

• Gene Names: KDM3A; TSGA; JMJD1; JHDM2A; JHMD2A; JMJD1A
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: JMJD1A Antibody is affinity chromatography purified via peptide column.
• Synonyms: JMJD1A, Antibody; JMJD1A Antibody; JMJD1A; TSGA; JMJD1; JHDM2A; JHMD2A; KIAA0742; Lysine-specific demethylase 3A; JmjC domain-containing histone demethylation protein 2A; lysine (K)-specific demethylase 3A; anti-KDM3A antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This antibody will not cross-react with JMJD1B or JMJD1C.
• Purity/Purification: JMJD1A Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1321

• Applicable Applications for anti-KDM3A antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: JMJD1A antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human JMJD1A.
• Buffer: JMJD1A Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: JMJD1A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of JMJD1A in Rat Liver cells with JMJD1A antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of JMJD1A in rat liver tissue with JMJD1A antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of JMJD1A in HepG2 cell lysate with JMJD1A antibody at 1 μg/mL.)

Related Product Information for anti-KDM3A antibody

JMJD1A Antibody: The jumonji domain containing 1A protein (JMJD1A) was originally discovered as a testes specific gene, but has been found to be expressed in numerous tissues. JMJD1A is a histone demethylase and specifically demethylates mono- and dimethyl-H3K9. It has also been found to be a novel interaction partner with ER71, a transcription factor expressed in the testes of adult mice and during embryogenesis. JMJD1A is also a downstream gene of STAT3, a protein that has been found to be important in the maintenance of mouse embryonic stem (mES) cells, and decreased JMJD1A expression correlated with the differentiation of cultured mES cells following the removal of the cytokine LIF. These findings suggest that JMJD1A might be a critical signaling molecule underlying the maintenance of pluripotency in embryonic stem cells. At least two isoforms of JMJD1A are known to exist.

NCBI and Uniprot Product Information

• NCBI GI #: 20357522
• NCBI GeneID: 55818
• NCBI Accession #: NP_060903
• NCBI GenBank Nucleotide #: NM_018433.5
• UniProt Accession #: Q9Y4C1; Q53S72; Q68D47; Q68UT9; Q6N050; Q8IY08; D6W5M3
• Molecular Weight: 147,341 Da
• NCBI Official Full Name: lysine-specific demethylase 3A
• NCBI Official Synonym Full Names: lysine (K)-specific demethylase 3A
• NCBI Official Symbol: KDM3A
• NCBI Official Synonym Symbols: TSGA; JMJD1; JHDM2A; JHMD2A; JMJD1A
• NCBI Protein Information: lysine-specific demethylase 3A; testis-specific protein A; jumonji domain containing 1; jumonji domain containing 1A; jumonji domain-containing protein 1A; jumonji C domain-containing histone demethylase 2A; jmjC domain-containing histone demethylation protein 2A
• UniProt Protein Name: Lysine-specific demethylase 3A
• UniProt Gene Name: KDM3A
• UniProt Synonym Gene Names: JHDM2A; JMJD1; JMJD1A; KIAA0742; TSGA
• UniProt Entry Name: KDM3A_HUMAN