Rabbit Junction plakoglobin Polyclonal Antibody | anti-JUP antibody
Anti-gamma Catenin Antibody
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunohistochemistry (Paraffin-embedded Section): Concentration: 0.5-1mug/ml; Tested Species: Human, Mouse, Rat
Immunohistochemistry (Frozen Section): Concentration: 0.5-1mug/ml; Tested Species: Rat; Predicted Species: Human
IHC (Immunohistchemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(F)IHC(F): Rat Intestine Tissue)
IHC (Immunohistochemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(P)IHC(P): Rat Intestine Tissue)
IHC (Immunohistochemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(P)IHC(P): Mouse Intestine Tissue)
IHC (Immunohistochemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
WB (Western Blot)
(Anti- gamma Catenin Picoband antibody, AAA11635, Western blottingAll lanes: Anti gamma Catenin (AAA11635) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: Rat Cardiac Muscle Tissue Lysate at 50ugLane 3: Rat Thymus Tissue Lysate at 50ugLane 4: RH35 Whole Cell Lysate at 40ugLane 5: Hela Whole Cell Lysate at 40ugLane 6: Colo320 Whole Cell Lysate at 40ugLane 7: HepG2 Whole Cell Lysate at 40ugLane 8: HepA Whole Cell Lysate at 40ugLane 9: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 81KD Observed bind size: 81KD)
Background: Junction plakoglobin(JUP), also known as gamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to beta-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Meanwhile, JUP may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.