IHC (Immunohiostchemistry)
(Immunohistochemistry of KAI1 in human colon tissue with KAI1 antibody at 2.5 ug/mL.)
Rabbit KAI1 Polyclonal Antibody | anti-KAI1 antibody
KAI1 Antibody
Gene Names
CD82; R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
KAI1, Antibody; KAI1 Antibody; CD82 antigen, tetraspanin-27, Tspan-27, suppressor of tumorgenicity-6; anti-KAI1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
267
Applicable Applications for anti-KAI1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 15 amino acid peptide from near the carboxy terminus of human KAI1.
Target Name
KAI1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of KAI1 in human colon tissue with KAI1 antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of KAI1 in human colon tissue with KAI1 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of KAI1 in A549 cell lysate with KAI1 antibody at (A) 0.5 and (B) 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of KAI1 in A549 cell lysate with KAI1 antibody at (A) 0.5 and (B) 1 ug/mL.)
Related Product Information for anti-KAI1 antibody
KAI1 was initially identified from a T-cell activation study as a four-transmembrane protein that plays an accessory role in T-cell activation, and was later determined to act as a cancer metastasis suppressor gene. This protein is ubiquitously expressed at moderate to high levels in most tissues, but its expression is downregulated during tumor progression. The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients. Recently, KAI1 was found to interact with DARC, the Duffy antigen for chemokines using a yeast two hybrid screen. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases. At least two isoforms of KAI1 are known to exist.
Product Categories/Family for anti-KAI1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,818 Da
NCBI Official Full Name
CD82 antigen isoform 1
NCBI Official Synonym Full Names
CD82 molecule
NCBI Official Symbol
CD82
NCBI Official Synonym Symbols
R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27
NCBI Protein Information
CD82 antigen
UniProt Protein Name
CD82 antigen
UniProt Gene Name
CD82
UniProt Synonym Gene Names
KAI1; SAR2; ST6; TSPAN27; Tspan-27
UniProt Entry Name
CD82_HUMAN
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Product Notes
The KAI1 cd82 (Catalog #AAA306615) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KAI1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KAI1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the KAI1 cd82 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KAI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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