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product-image-AAA201730_WB10.jpg WB (Western Blot) (Human A549 Whole Cell)

Rabbit KDR Polyclonal Antibody | anti-KDR antibody

KDR antibody - N-terminal region

Gene Names
KDR; FLK1; CD309; VEGFR; VEGFR2
Reactivity
Tested Reactivity: Human
Predicted Reactivity: Cow, Dog, Horse, Human, Pig
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purified
Synonyms
KDR, Antibody; KDR antibody - N-terminal region; anti-KDR antibody
Ordering
Host
Rabbit
Reactivity
Tested Reactivity: Human
Predicted Reactivity: Cow, Dog, Horse, Human, Pig
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml (varies by lot)
Applicable Applications for anti-KDR antibody
WB (Western Blot), IHC (Immunohistochemistry)
Protein Size (# AA)
1356 amino acids
Protein Interactions
FBXO25; VEGFA; MYO1C; CAV1; NPM1; EPN1; SRC; CBL; IQGAP1; UBC; CSNK1D; FBXW11; BTRC; CUL1; AIMP2; SHC2; SYNGAP1; ACP1; ATR; FRS2; SH2D2A; DNM2; NRP1; VEGFC; GRB10; CDH5; GNAQ; SHC1; STAT1; NCK1; SHB; PLCG2; P2RY2; BMX; FIGF; KDR; TIMP3; PTPN6; PTPN11; ITG
Blocking Peptide
For anti-KDR (MBS3224531) antibody is MBS3225050
Predicted Homology
Cow: 86%; Dog: 100%; Horse: 100%; Human: 100%; Pig: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human KDR.
Replacement Item
This antibody may replace item sc-19530 from Santa Cruz Biotechnology.
Preparation and Storage
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

WB (Western Blot)

(Human A549 Whole Cell)

product-image-AAA201730_WB10.jpg WB (Western Blot) (Human A549 Whole Cell)

WB (Western Blot)

(WB Suggested Anti-KDR Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Lung)

product-image-AAA201730_WB11.jpg WB (Western Blot) (WB Suggested Anti-KDR Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Lung)

IHC (Immunohiostchemistry)

(Researcher: Department of Pathology, Hospital de Carabineros de Chile, Santiago, ChileApplication: IHCSpecies+tissue/cell type: Control-Human Placenta, Sample-Human colorectal cancerPrimary antibody dilution: 1:100Secondary antibody: Biotinylated pig anti-rabbit+streptavidin-HRP)

product-image-AAA201730_IHC13.jpg IHC (Immunohiostchemistry) (Researcher: Department of Pathology, Hospital de Carabineros de Chile, Santiago, ChileApplication: IHCSpecies+tissue/cell type: Control-Human Placenta, Sample-Human colorectal cancerPrimary antibody dilution: 1:100Secondary antibody: Biotinylated pig anti-rabbit+streptavidin-HRP)

IHC (Immunohistochemistry)

(KDR in endothelial cells in blood vessels in placenta was detected using HRP/AEC red color stain.recommended for IHC on human tissue.5-10 ug/mL)

product-image-AAA201730_IHC15.jpg IHC (Immunohistochemistry) (KDR in endothelial cells in blood vessels in placenta was detected using HRP/AEC red color stain.recommended for IHC on human tissue.5-10 ug/mL)
Related Product Information for anti-KDR antibody
KDR is the receptor for VEGF or VEGFC. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
151kDa
NCBI Official Full Name
vascular endothelial growth factor receptor 2
NCBI Official Synonym Full Names
kinase insert domain receptor
NCBI Official Symbol
KDR
NCBI Official Synonym Symbols
FLK1; CD309; VEGFR; VEGFR2
NCBI Protein Information
vascular endothelial growth factor receptor 2
UniProt Protein Name
Vascular endothelial growth factor receptor 2
UniProt Gene Name
KDR
UniProt Synonym Gene Names
FLK1; VEGFR2; VEGFR-2; FLK-1; KDR
UniProt Entry Name
VGFR2_HUMAN

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Product Notes

The KDR kdr (Catalog #AAA201730) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KDR antibody - N-terminal region reacts with Tested Reactivity: Human Predicted Reactivity: Cow, Dog, Horse, Human, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's KDR can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the KDR kdr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KDR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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