ICC (Immunocytochemistry)
(Immunocytochemistry of KPNA1 in HeLa cells with KPNA1 antibody at 2.5 ug/mL.)
Rabbit KPNA1 Polyclonal Antibody | anti-KPNA1 antibody
KPNA1 Antibody
Gene Names
KPNA1; RCH2; SRP1; IPOA5; NPI-1
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
KPNA1, Antibody; KPNA1 Antibody; Karyopherin alpha 1 Nucleoprotein interactor 1, Importin alpha 5, IPOA5, RAG cohort protein 2, RCH2, SRP1, NPI-1; anti-KPNA1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
538
Applicable Applications for anti-KPNA1 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 15 amino acid peptide near the amino terminus of human KPNA1.
Target Name
KPNA1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of KPNA1 in HeLa cells with KPNA1 antibody at 2.5 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of KPNA1 in HeLa cells with KPNA1 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of KPNA1 in Hela cell lysate with KPNA1 antibody at 1ug/mL.)
WB (Western Blot)
(Western blot analysis of KPNA1 in Hela cell lysate with KPNA1 antibody at 1ug/mL.)
Related Product Information for anti-KPNA1 antibody
Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA1, also known as importin alpha 5, is the alpha subunit of karyopherin, which forms a complex with importin subunit beta-1 and functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. It is ubiquitously expressed and polyubiquitinated in the presence of RAG1. KPNA1 interacts with various virus nucleoproteins, including those of Ebola and influenza.
Product Categories/Family for anti-KPNA1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
60,222 Da
NCBI Official Full Name
importin subunit alpha-5
NCBI Official Synonym Full Names
karyopherin alpha 1 (importin alpha 5)
NCBI Official Symbol
KPNA1
NCBI Official Synonym Symbols
RCH2; SRP1; IPOA5; NPI-1
NCBI Protein Information
importin subunit alpha-5
UniProt Protein Name
Importin subunit alpha-5
UniProt Gene Name
KPNA1
UniProt Synonym Gene Names
RCH2; NPI-1
UniProt Entry Name
IMA5_HUMAN
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Product Notes
The KPNA1 kpna1 (Catalog #AAA301558) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KPNA1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KPNA1 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the KPNA1 kpna1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KPNA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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