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IHC (Immunohistochemistry)
(Detection of human KPNA3 by IHC-IF. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-KPNA3 (Cat. No. AAA213952) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody used at a dilution of 1:100.)
Rabbit anti-Human, Mouse KPNA3 Polyclonal Antibody | anti-KPNA3 antibody
Rabbit anti-KPNA3 IHC Antibody, Affinity Purified
Gene Names
KPNA3; SRP1; SRP4; IPOA4; hSRP1; SRP1gamma
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
KPNA3, Antibody; Rabbit anti-KPNA3 IHC Antibody, Affinity Purified; importin subunit alpha-4; SRP4; SRP1-gamma; SRP1gamma; SRP1; qip2; Karyopherin subunit alpha-3; hSRP1; IPOA4; importin subunit alpha-3; importin alpha-3; importin alpha Q2; importin alpha 4; karyopherin alpha 3 (importin alpha 4); Importin subunit alpha-4; karyopherin subunit alpha 3; anti-KPNA3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Concentration
250ug/ml (varies by lot)
Applicable Applications for anti-KPNA3 antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Predicted Reactivity
Monkey, Chimpanzee, Small-eared galago, White-tufted-ear marmoset
Immunogen
Between 1 and 50
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
IHC (Immunohistochemistry)
(Detection of human KPNA3 by IHC-IF. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-KPNA3 (Cat. No. AAA213952) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody used at a dilution of 1:100.)
IHC (Immunohistochemistry)
(Detection of human KPNA3 by IHC-IF. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-KPNA3 (Cat. No. AAA213952) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody used at a dilution of 1:100.)
IHC (Immunohistochemisry)
(Detection of human KPNA3 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-KPNA3 (Cat. No. AAA213952) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohistochemisry)
(Detection of human KPNA3 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-KPNA3 (Cat. No. AAA213952) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohiostchemistry)
(Detection of human KPNA3 by immunohistochemistry. Sample: FFPE section of human testis. Antibody: Affinity purified rabbit anti-KPNA3 (Cat. No. AAA213952) used at a dilution of 1:500. Detection: DAB)
IHC (Immunohiostchemistry)
(Detection of human KPNA3 by immunohistochemistry. Sample: FFPE section of human testis. Antibody: Affinity purified rabbit anti-KPNA3 (Cat. No. AAA213952) used at a dilution of 1:500. Detection: DAB)
IHC (Immunohistochemistry)
(Detection of mouse KPNA3 by immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-KPNA3 (Cat. No. AAA213952) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohistochemistry)
(Detection of mouse KPNA3 by immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-KPNA3 (Cat. No. AAA213952) used at a dilution of 1:250. Detection: DAB)
Related Product Information for anti-KPNA3 antibody
KPNA3 (karyopherin alpha 3), also known as importin alpha 4, is a member of the importin alpha family of proteins which includes KPNA1 (importin alpha 5), KPNA2 (importin alpha 1), KPNA3 (importin alpha 4), KPNA4 (importin alpha 3), KPNA5 (importin alpha 6), and KPNA6 (importin alpha 7). The importin alpha family of proteins plays a role in the import of proteins from the cytoplasm to the nucleus. The import of proteins from the cytoplasm to the nucleus involves docking the protein to receptors associated with the nuclear pore complex (NPC) followed by translocation through the nuclear pore. Importin alpha proteins bind the nuclear localization signal (NLS) of cargo proteins and function as adaptor proteins for the nuclear pore receptor KPNB1 (importin beta 1). KPNB1 is responsible for docking the importin-cargo complex to the cytoplasmic side of the NPC for its translocation through the NPC. KPNA3 (Importin alpha 4) and KPNA4 (importin alpha 3) have been reported to mediate the nuclear import of TNF-alpha induced nuclear import of NF-kappaB p50/p65 heterodimers. KPNA3 has also been reported to be responsible for the ligand-independent nuclear translocation of the vitamin D receptor.
Product Categories/Family for anti-KPNA3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,811 Da
NCBI Official Full Name
importin subunit alpha-4
NCBI Official Synonym Full Names
karyopherin alpha 3 (importin alpha 4)
NCBI Official Symbol
KPNA3
NCBI Official Synonym Symbols
SRP1; SRP4; IPOA4; hSRP1; SRP1gamma
NCBI Protein Information
importin subunit alpha-4; qip2; SRP1-gamma; importin alpha 4; importin alpha-3; importin alpha Q2; importin-alpha-Q2; importin subunit alpha-3; karyopherin subunit alpha-3
UniProt Protein Name
Importin subunit alpha-4
UniProt Gene Name
KPNA3
UniProt Synonym Gene Names
QIP2; Qip2
UniProt Entry Name
IMA4_HUMAN
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Product Notes
The KPNA3 kpna3 (Catalog #AAA213952) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-KPNA3 IHC Antibody, Affinity Purified reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KPNA3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the KPNA3 kpna3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KPNA3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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