ICC (Immunocytochemistry)
(Immunocytochemistry of LAMP-2 in HepG2 cells with LAMP-2 antibody at 10 ug/mL.)
Rabbit anti-Human, Mouse LAMP-2 Polyclonal Antibody | anti-LAMP-2 antibody
LAMP-2 Antibody
Gene Names
LAMP2; LAMPB; CD107b; LAMP-2; LGP110
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
LAMP-2, Antibody; LAMP-2 Antibody; LAMP-2, Lysosome associated membrane protein 2; anti-LAMP-2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
410
Applicable Applications for anti-LAMP-2 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide from near the carboxy terminus ofhuman LAMP-2.
Target Name
LAMP-2
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of LAMP-2 in HepG2 cells with LAMP-2 antibody at 10 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of LAMP-2 in HepG2 cells with LAMP-2 antibody at 10 ug/mL.)
WB (Western Blot)
(Western blot analysis of LAMP-2 in HepG2 cell lysate with LAMP-2 antibody at (A) 1 and (B) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of LAMP-2 in HepG2 cell lysate with LAMP-2 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-LAMP-2 antibody
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin). LAMP-2, a highly glycosylated protein associated with the lysosome, has recently been shown to be important in autophagy as mice deficient in this protein failed to convert autophagic vacuoles into vacuoles leading to impaired degradation of long-lived proteins. This correlates with the finding that human LAMP-2 deficiency causing Danon's disease is associated with the accumulation of autophagic material in striated myocytes. LAMP-2 exists in multiple isoforms.
Product Categories/Family for anti-LAMP-2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,170 Da
NCBI Official Full Name
lysosome-associated membrane glycoprotein 2 isoform B
NCBI Official Synonym Full Names
lysosomal-associated membrane protein 2
NCBI Official Symbol
LAMP2
NCBI Official Synonym Symbols
LAMPB; CD107b; LAMP-2; LGP110
NCBI Protein Information
lysosome-associated membrane glycoprotein 2
UniProt Protein Name
Lysosome-associated membrane glycoprotein 2
UniProt Gene Name
LAMP2
UniProt Synonym Gene Names
LAMP-2; Lysosome-associated membrane protein 2
UniProt Entry Name
LAMP2_HUMAN
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Product Notes
The LAMP-2 lamp2 (Catalog #AAA306188) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LAMP-2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LAMP-2 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the LAMP-2 lamp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAMP-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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