WB (Western Blot)
(LARS Antibody (N-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the LARS antibody detected the LARS protein (arrow).)
Rabbit anti-Mouse LARS Polyclonal Antibody | anti-LARS antibody
LARS Antibody (N-term)
Gene Names
LARS; LRS; LEUS; LFIS; ILFS1; LARS1; LEURS; PIG44; RNTLS; HSPC192; hr025Cl
Reactivity
Mouse
Applications
Western Blot, ELISA, Flow Cytometry, Functional Assay
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
LARS, Antibody; LARS Antibody (N-term); Leucine--tRNA ligase; cytoplasmic; Leucyl-tRNA synthetase; LeuRS; LARS; KIAA1352; anti-LARS antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This LARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-205 amino acids from the N-terminal region of human LARS.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
176-205
Sequence Length
485
Applicable Applications for anti-LARS antibody
WB (Western Blot), ELISA, FCM/FACS (Flow Cytometry)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(LARS Antibody (N-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the LARS antibody detected the LARS protein (arrow).)
WB (Western Blot)
(LARS Antibody (N-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the LARS antibody detected the LARS protein (arrow).)
FCM/FACS (Flow Cytometry)
(LARS Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(LARS Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-LARS antibody
This gene encodes a cytosolic leucine-tRNA synthetase, a
member of the class I aminoacyl-tRNA synthetase family. The encoded
enzyme catalyzes the ATP-dependent ligation of L-leucine to
tRNA(Leu). It is found in the cytoplasm as part of a
multisynthetase complex and interacts with the arginine tRNA
synthetase through its C-terminal domain. Alternatively spliced
transcript variants of this gene have been found; however, their
full-length nature is not known.
member of the class I aminoacyl-tRNA synthetase family. The encoded
enzyme catalyzes the ATP-dependent ligation of L-leucine to
tRNA(Leu). It is found in the cytoplasm as part of a
multisynthetase complex and interacts with the arginine tRNA
synthetase through its C-terminal domain. Alternatively spliced
transcript variants of this gene have been found; however, their
full-length nature is not known.
References
Pang, Y.L., et al. Biochemistry 48(38):8958-8964(2009)
Seiradake, E., et al. J. Mol. Biol. 390(2):196-207(2009)
Shin, S.H., et al. Exp. Mol. Med. 40(2):229-236(2008)
Maeso, E., et al. Neuromuscul. Disord. 17(5):415-418(2007)
Lue, S.W., et al. Biochemistry 46(15):4466-4472(2007)
Seiradake, E., et al. J. Mol. Biol. 390(2):196-207(2009)
Shin, S.H., et al. Exp. Mol. Med. 40(2):229-236(2008)
Maeso, E., et al. Neuromuscul. Disord. 17(5):415-418(2007)
Lue, S.W., et al. Biochemistry 46(15):4466-4472(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
134466
NCBI Official Full Name
leucine--tRNA ligase, cytoplasmic
NCBI Official Synonym Full Names
leucyl-tRNA synthetase
NCBI Official Symbol
LARS
NCBI Official Synonym Symbols
LRS; LEUS; LFIS; ILFS1; LARS1; LEURS; PIG44; RNTLS; HSPC192; hr025Cl
NCBI Protein Information
leucine--tRNA ligase, cytoplasmic
UniProt Protein Name
Leucine--tRNA ligase, cytoplasmic
UniProt Gene Name
LARS
UniProt Synonym Gene Names
KIAA1352; LeuRS
UniProt Entry Name
SYLC_HUMAN
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Product Notes
The LARS lars (Catalog #AAA287400) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 176-205. The LARS Antibody (N-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LARS can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the LARS lars for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LARS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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