Rabbit anti-Human, Mouse LGI2 Polyclonal Antibody | anti-Lgi2 antibody

LGI2 Antibody

Cat. Num. AAA40285

• Gene Names: Lgi2; mKIAA1916
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: LGI2 Antibody is affinity chromatography purified via peptide column.
• Synonyms: LGI2, Antibody; LGI2 Antibody; LGI2; mKIAA1916; Kiaa1916; Leucine-rich repeat LGI family member 2; Leucine-rich glioma-inactivated protein 2; leucine-rich repeat LGI family, member 2; anti-Lgi2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This LGI2 antibody is predicted to be specific to LGI2 and not recognize other LGI proteins.Three isoforms of LGI2 are known to exist; this LGI2 antibody will recognize only the longest.
• Purity/Purification: LGI2 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 550

• Applicable Applications for anti-Lgi2 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: LGI2 antibody was raised against a 10 amino acid synthetic peptide from near the center of human LGI2.
• Buffer: LGI2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: LGI2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of LGI2 in Human Brain cells with LGI2 antibody at 5 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemical staining of human brain tissue using LGI2 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of LGI2 in mouse liver tissue lysate with LGI2 antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-Lgi2 antibody

LGI2 Antibody: The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.

NCBI and Uniprot Product Information

• NCBI GI #: 32469737
• NCBI GeneID: 246316
• UniProt Accession #: Q8K4Z0; Q80T76
• Molecular Weight: 62,012 Da
• NCBI Official Full Name: Leucine-rich repeat LGI family member 2
• NCBI Official Synonym Full Names: leucine-rich repeat LGI family, member 2
• NCBI Official Symbol: Lgi2
• NCBI Official Synonym Symbols: mKIAA1916
• NCBI Protein Information: leucine-rich repeat LGI family member 2; leucine-rich glioma-inactivated protein 2
• UniProt Protein Name: Leucine-rich repeat LGI family member 2
• UniProt Gene Name: Lgi2
• UniProt Synonym Gene Names: Kiaa1916
• UniProt Entry Name: LGI2_MOUSE