WB (Western Blot)
(WB Suggested Anti-LIN28 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate)
Rabbit LIN28 Polyclonal Antibody | anti-LIN28A antibody
LIN28 antibody - N-terminal region
Gene Names
LIN28A; CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A
Reactivity
Tested: HumanPredicted: Cow, Dog, Goat, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Sheep, Yeast
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purified
Synonyms
LIN28, Antibody; LIN28 antibody - N-terminal region; anti-LIN28A antibody
Host
Rabbit
Reactivity
Tested: Human
Predicted: Cow, Dog, Goat, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Sheep, Yeast
Predicted: Cow, Dog, Goat, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Sheep, Yeast
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration
0.5mg/ml (varies by lot)
Sequence
Synthetic peptide located within the following region: GSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRM
Sequence Length
209
Applicable Applications for anti-LIN28A antibody
WB (Western Blot), IHC (Immunohistochemistry)
Predicted Homology Based on Immunogen Sequence
Cow: 100%; Dog: 100%; Goat: 91%; Guinea Pig: 86%; Human: 100%; Mouse: 90%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 77%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human LIN28
Protein Size (#AA)
209 Amino Acids
Protein Interactions
HNRNPUL2; HNRNPA3; DHX36; SREK1; TRIM71; LARP4; TGS1; DHX57; GADD45GIP1; LTV1; NOA1; DDX50; KRI1; NOL6; METTL17; NOC3L; ZC3HAV1; PPAN; CCBL2; MEPCE; TSR1; NHP2; NOP10; STRBP; BRIX1; RBM28; PHAX; SRRT; LARP7; DDX41; HP1BP3; NOB1; PRPF19; ZBTB11; SND1; AATF
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(WB Suggested Anti-LIN28 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate)
WB (Western Blot)
(WB Suggested Anti-LIN28 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate)
IHC (Immunohistochemistry)
(Immunohistochemistry with Human Testis lysate tissue at an antibody concentration of 5.0ug/ml using anti-LIN28 antibody)
IHC (Immunohistochemistry)
(Immunohistochemistry with Human Testis lysate tissue at an antibody concentration of 5.0ug/ml using anti-LIN28 antibody)
Related Product Information for anti-LIN28A antibody
This is a rabbit polyclonal antibody against LIN28. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.
Target Description: LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.
Product Categories/Family for anti-LIN28A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23kDa
NCBI Official Full Name
protein lin-28 homolog A
NCBI Official Synonym Full Names
lin-28 homolog A
NCBI Official Symbol
LIN28A
NCBI Official Synonym Symbols
CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A
NCBI Protein Information
protein lin-28 homolog A
UniProt Protein Name
Protein lin-28 homolog A
UniProt Gene Name
LIN28A
UniProt Synonym Gene Names
CSDD1; LIN28; ZCCHC1; Lin-28A
UniProt Entry Name
LN28A_HUMAN
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Product Notes
The LIN28A lin28a (Catalog #AAA197816) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LIN28 antibody - N-terminal region reacts with Tested: Human Predicted: Cow, Dog, Goat, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Sheep, Yeast and may cross-react with other species as described in the data sheet. AAA Biotech's LIN28 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the LIN28A lin28a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: GSVSNQQFAG GCAKAAEEAP EEAPEDAARA ADEPQLLHGA GICKWFNVRM. It is sometimes possible for the material contained within the vial of "LIN28, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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