IF (Immunofluorescence)
(Immunofluorescence of LNPEP in human lung tissue with LNPEP antibody at 20 μg/mL.)
Rabbit anti-Human LNPEP Polyclonal Antibody | anti-LNPEP antibody
LNPEP Antibody
Gene Names
LNPEP; CAP; IRAP; PLAP; P-LAP
Reactivity
Human
Applications
Immunofluorescence, Western Blot, ELISA
Purity
LNPEP Antibody is affinity chromatography purified via peptide column.
Synonyms
LNPEP, Antibody; LNPEP Antibody; LNPEP; CAP; IRAP; PLAP; P-LAP; OTASE; Leucyl-cystinyl aminopeptidase; Insulin-regulated membrane aminopeptidase; Cystinyl aminopeptidase; leucyl/cystinyl aminopeptidase; anti-LNPEP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
At least three isoforms are known to exist; this antibody will detect all three isoforms. Despite its predicted molecular weight, LNPEP often migrates at 165kD in SDS-PAGE.
Purity/Purification
LNPEP Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1025
Applicable Applications for anti-LNPEP antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
LNPEP antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human LNPEP.
Buffer
LNPEP Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
LNPEP antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of LNPEP in human lung tissue with LNPEP antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of LNPEP in human lung tissue with LNPEP antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of LNPEP in human lung tissue lysate with LNPEP antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of LNPEP in human lung tissue lysate with LNPEP antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-LNPEP antibody
LNPEP Antibody: LNPEP, also known as insulin-responsive aminopeptidase (IRAP), was initially identified as an abundant protein that is associated with specialized endosomes termed GLUT4 storage vesicles (GSVs) in adipocytes. The luminal domain of LNPEP contains an aminopeptidase activity that is involved in peptide hormone processing and antigenic peptide processing. LNPEP is also a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to the GSVs.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
113 kDa
NCBI Official Full Name
leucyl-cystinyl aminopeptidase isoform 1
NCBI Official Synonym Full Names
leucyl/cystinyl aminopeptidase
NCBI Official Symbol
LNPEP
NCBI Official Synonym Symbols
CAP; IRAP; PLAP; P-LAP
NCBI Protein Information
leucyl-cystinyl aminopeptidase; otase; oxytocinase; vasopressinase; AT (4) receptor; angiotensin IV receptor; insulin-regulated aminopeptidase; placental leucine aminopeptidase; insulin-responsive aminopeptidase; insulin-regulated membrane aminopeptidase
UniProt Protein Name
Leucyl-cystinyl aminopeptidase
UniProt Gene Name
LNPEP
UniProt Synonym Gene Names
OTASE; Cystinyl aminopeptidase; IRAP; OTase; P-LAP
UniProt Entry Name
LCAP_HUMAN
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Product Notes
The LNPEP lnpep (Catalog #AAA40524) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LNPEP Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LNPEP can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the LNPEP lnpep for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LNPEP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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