Rabbit anti-Human LRRFIP1 Polyclonal Antibody | anti-LRRFIP1 antibody

LRRFIP1 Antibody

Cat. Num. AAA40171

• Gene Names: LRRFIP1; GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1
• Reactivity: Human
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: LRRFIP1 Antibody is affinity chromatography purified via peptide column.
• Synonyms: LRRFIP1, Antibody; LRRFIP1 Antibody; LRRFIP1; GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1; Leucine-rich repeat flightless-interacting protein 1; GC-binding factor 2; LRR FLII-interacting protein 1; leucine rich repeat (in FLII) interacting protein 1; anti-LRRFIP1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: LRRFIP1 antibody is predicted to not cross-react with other LRRFIP family members. Three isoforms of LRRFIP1 are known to exist; this antibody will only recognize the two longer isoforms.
• Purity/Purification: LRRFIP1 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 808

• Applicable Applications for anti-LRRFIP1 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: LRRFIP1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human LRRFIP1.
• Buffer: LRRFIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: LRRFIP1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of LRRFIP1 in human colon tissue with LRRFIP1 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of LRRFIP1 in human colon tissue with LRRFIP1 antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of LRRFIP1 in human colon tissue lysate with LRRFIP1 antibody at 1 μg/mL.)

Related Product Information for anti-LRRFIP1 antibody

LRRFIP1 Antibody: LRRFIP1, also known as GC-binding factor 2 (GCF2), is a 738 amino acid transcriptional repressor that mainly plays a cytoskeletal role. It is primarily localized in the cytoplasm and preferentially binds to GC-rich dsDNA, but will also bind directly to dsRNA as well. The RNA binding domain encompasses a lysine-rich motif. LRRFIP1 interacts with the mammalian Flightless I (Fli-I) and is a key component in the cytoskeletal regulation of platelet function. LRRFIP1 and the related protein LRRFIP2 may modulate canonical WNT signaling and mediate the IRF3-induced production of type I interferon via a beta-catenin-dependent pathway.

NCBI and Uniprot Product Information

• NCBI GI #: 212276096
• NCBI GeneID: 9208
• NCBI Accession #: NP_001131022
• NCBI GenBank Nucleotide #: NM_001137552.1
• UniProt Accession #: Q32MZ4; O75766; O75799; Q32MZ5; Q53T49; Q6PKG2; Q9Y607; E9PGZ2
• Molecular Weight: 73,060 Da
• NCBI Official Full Name: leucine-rich repeat flightless-interacting protein 1 isoform 3
• NCBI Official Synonym Full Names: leucine rich repeat (in FLII) interacting protein 1
• NCBI Official Symbol: LRRFIP1
• NCBI Official Synonym Symbols: GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1
• NCBI Protein Information: leucine-rich repeat flightless-interacting protein 1; GC-binding factor 2; NEDD8-conjugating enzyme; TAR RNA-interacting protein; LRR FLII-interacting protein 1
• UniProt Protein Name: Leucine-rich repeat flightless-interacting protein 1
• UniProt Gene Name: LRRFIP1
• UniProt Synonym Gene Names: GCF2; TRIP; LRR FLII-interacting protein 1
• UniProt Entry Name: LRRF1_HUMAN