Rabbit LRRFIP2 Polyclonal Antibody | anti-LRRFIP2 antibody

LRRFIP2 Antibody

Cat. Num. AAA39699

• Gene Names: LRRFIP2; HUFI-2
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: LRRFIP2 Antibody is affinity chromatography purified via peptide column.
• Synonyms: LRRFIP2, Antibody; LRRFIP2 Antibody; LRRFIP2; HUFI-2; Leucine-rich repeat flightless-interacting protein 2; LRR FLII-interacting protein 2; leucine rich repeat (in FLII) interacting protein 2; anti-LRRFIP2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Three isoforms of LRRFIP2 are known to exist; this antibody will recognize all three. LRRFIP2 antibody is predicted to not cross-react with other LRRFIP family members.
• Purity/Purification: LRRFIP2 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 721

• Applicable Applications for anti-LRRFIP2 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: LRRFIP2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRFIP2. The immunogen is located within amino acids 620-760 of LRRFIP2
• Buffer: LRRFIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Homology: Predicted species reactivity based on immunogen sequence: Bovine: (100%)
• Preparation and Storage: LRRFIP2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of LRRFIP2 in human colon tissue with LRRFIP2 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of LRRFIP2 in human colon tissue with LRRFIP2 antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of LRRFIP2 in rat colon tissue lysate with LRRFIP2 antibody at (A) 0.5 and (B) 1 μg/mL.)

Related Product Information for anti-LRRFIP2 antibody

LRRFIP2 Antibody: The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-κB during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.

NCBI and Uniprot Product Information

• NCBI GI #: 5453726
• NCBI GeneID: 9209
• NCBI Accession #: NP_006300
• NCBI GenBank Nucleotide #: NM_006309.3
• UniProt Accession #: Q9Y608; Q68CV3; Q9NXH5; A8K649; A8MXR0; B4DY63
• NCBI Official Full Name: leucine-rich repeat flightless-interacting protein 2 isoform 1
• NCBI Official Synonym Full Names: leucine rich repeat (in FLII) interacting protein 2
• NCBI Official Symbol: LRRFIP2
• NCBI Official Synonym Symbols: HUFI-2
• NCBI Protein Information: leucine-rich repeat flightless-interacting protein 2; LRR FLII-interacting protein 2
• UniProt Protein Name: Leucine-rich repeat flightless-interacting protein 2
• UniProt Gene Name: LRRFIP2
• UniProt Synonym Gene Names: LRR FLII-interacting protein 2
• UniProt Entry Name: LRRF2_HUMAN