WB (Western Blot)
(Mouse Maf Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Maf antibody detected the Maf protein (arrow).)
Rabbit Maf Polyclonal Antibody | anti-Maf antibody
Mouse Maf Antibody (N-term)
Gene Names
Maf; c-maf; AW047063; 2810401A20Rik; A230108G15Rik
Reactivity
Mouse (Predicted Reactivity: Bovine, Chicken, Human, Rat)
Applications
ELISA, Western Blot
Purity
This antibody is
purified through a protein A column, followed by peptide affinity purification.
Synonyms
Maf, Antibody; Mouse Maf Antibody (N-term); Transcription factor Maf; Proto-oncogene c-Maf; V-maf musculoaponeurotic fibrosarcoma oncogene homolog; Maf; Maf2; anti-Maf antibody
Host
Rabbit
Reactivity
Mouse (Predicted Reactivity: Bovine, Chicken, Human, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Maf antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of mouse Maf.
Purity/Purification
This antibody is
purified through a protein A column, followed by peptide affinity purification.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Positions
14-42
Sequence Length
370
Applicable Applications for anti-Maf antibody
ELISA, WB (Western Blot)
Cellular Location
Nucleus.
Tissue Location
Expressed in tubules of the renal cortex and hepatocytes. Expressed in the lens (at protein level). Expressed in pancreatic islets and endothelial cells.
Precautions
Mouse Maf Antibody (N-term) is for research use only
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Mouse Maf Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Maf antibody detected the Maf protein (arrow).)
WB (Western Blot)
(Mouse Maf Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Maf antibody detected the Maf protein (arrow).)
Related Product Information for anti-Maf antibody
Maf acts as a transcriptional activator or repressor. When overexpressed, represses anti-oxidant response element (ARE)-mediated transcription. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Binds to the ARE sites of detoxifying enzyme gene promoters (By similarity). Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element. Activates transcription of the CD13 proximal promoter in endothelial cells. Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction. Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. Binds to the sequence 5'-[GT]G[GC]N[GT]AGNN-3' in the L7 promoter. Binds to the T-MARE (Maf response element) sites of lens-specific alpha-and beta-crystallin gene promoters. Binds element G1 on the glucagon promoter. Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells. It may interact with additional basic-zipper proteins that determine a subtype of Maf-responsive element binding.
Product Categories/Family for anti-Maf antibody
References
Nishikawa, K., et al. J. Clin. Invest. 120(10):3455-3465(2010)
Apetoh, L., et al. Nat. Immunol. 11(9):854-861(2010)
Wang, W.L., et al. Mol. Biol. Cell 21(14):2453-2468(2010)
Honma, Y., et al. Development 137(14):2319-2328(2010)
Wiley, L.A., et al. Invest. Ophthalmol. Vis. Sci. 51(7):3611-3618(2010)
Apetoh, L., et al. Nat. Immunol. 11(9):854-861(2010)
Wang, W.L., et al. Mol. Biol. Cell 21(14):2453-2468(2010)
Honma, Y., et al. Development 137(14):2319-2328(2010)
Wiley, L.A., et al. Invest. Ophthalmol. Vis. Sci. 51(7):3611-3618(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38435
NCBI Official Full Name
transcription factor Maf
NCBI Official Synonym Full Names
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
NCBI Official Symbol
Maf
NCBI Official Synonym Symbols
c-maf; AW047063; 2810401A20Rik; A230108G15Rik
NCBI Protein Information
transcription factor Maf
UniProt Protein Name
Transcription factor Maf
UniProt Gene Name
Maf
UniProt Synonym Gene Names
Maf2
UniProt Entry Name
MAF_MOUSE
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Product Notes
The Maf maf (Catalog #AAA283650) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 14-42. The Mouse Maf Antibody (N-term) reacts with Mouse (Predicted Reactivity: Bovine, Chicken, Human, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Maf can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the Maf maf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Maf, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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