Rabbit anti-Human MAPKAPK2 Polyclonal Antibody | anti-MAPKAPK2 antibody

MAPKAPK2 Antibody (N-term)

Cat. Num. AAA297736

• Gene Names: MAPKAPK2; MK2; MK-2; MAPKAP-K2
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Synonyms: MAPKAPK2, Antibody; MAPKAPK2 Antibody (N-term); MAP kinase-activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2; MAPKAPK2; Purified Rabbit Polyclonal Antibody (Pab); anti-MAPKAPK2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: This MAPKAPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-58 amino acids from the N-terminal region of human MAPKAPK2.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Applicable Applications for anti-MAPKAPK2 antibody: IHC (Immunohistochemistry), WB (Western Blot)
• Antigen Source: Human
• Antigen Type: Synthetic Peptide
• Antigen Region: 28-58
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohistochemisry)

(IHC-P: 1:50~100Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)

WB (Western Blot)

(WB: 1:1000; MAPKAPK2 Antibody (F43) (#AAA297736) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MAPKAPK2 antibody detected the MAPKAPK2 protein (arrow).)

WB (Western Blot)

(WB: 1:1000; Western blot analysis of MAPKAPK2 (arrow) using MAPKAPK2 Antibody (N-term) (AAA297736).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MAPKAPK2 gene (Lane 2) (Origene Technologies).)

Related Product Information for anti-MAPKAPK2 antibody

MAPKAPK2 a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo.

Product Categories/Family for anti-MAPKAPK2 antibody

Primary Antibodies; Cardiovascular; Signal Transduction

References

Meng, W., et al., J. Biol. Chem. 277(40):37401-37405 (2002).Han, Q., et al., J. Biol. Chem. 277(50):48379-48385 (2002).Werz, O., et al., Proc. Natl. Acad. Sci. U.S.A. 97(10):5261-5266 (2000).Kotlyarov, A., et al., Nat. Cell Biol. 1(2):94-97 (1999).Craxton, A., et al., J. Immunol. 161(7):3225-3236 (1998).

NCBI and Uniprot Product Information

• NCBI GI #: 10863901
• NCBI GeneID: 9261
• NCBI Accession #: NP_004750.1; NP_116584.2
• NCBI GenBank Nucleotide #: NM_004759.4
• UniProt Accession #: P49137; Q5SY30; Q5SY41; Q8IYD6
• Molecular Weight: 45,568 Da
• NCBI Official Full Name: MAP kinase-activated protein kinase 2 isoform 1
• NCBI Official Synonym Full Names: mitogen-activated protein kinase-activated protein kinase 2
• NCBI Official Symbol: MAPKAPK2
• NCBI Official Synonym Symbols: MK2; MK-2; MAPKAP-K2
• NCBI Protein Information: MAP kinase-activated protein kinase 2; MAPKAP kinase 2; MAPK-activated protein kinase 2
• UniProt Protein Name: MAP kinase-activated protein kinase 2
• UniProt Gene Name: MAPKAPK2
• UniProt Synonym Gene Names: MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2
• UniProt Entry Name: MAPK2_HUMAN