Rabbit MEF2A Polyclonal Antibody | anti-MEF2A antibody

MEF2A (Ab-312) Antibody

Cat. Num. AAA302127

• Gene Names: MEF2A; mef2; ADCAD1; RSRFC4; RSRFC9
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• Synonyms: MEF2A, Antibody; MEF2A (Ab-312) Antibody; MEF2; Serum response factor-like protein 1; anti-MEF2A antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total MEF2A protein.
• Purity/Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 497

• Applicable Applications for anti-MEF2A antibody: IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen Type: Peptide-KLH
• Immunogen Description: Peptide sequence around aa.310~314 (L-A-T-P-V) derived from Human MEF2A.
• Target Name: MEF2a
• Preparation and Storage: Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MEF2A(Ab-312) Antibody (left) or the same antibody preincubated with blocking peptide(right).)

WB (Western Blot)

(Western blot analysis of extracts from 3T3 cells using MEF2A(Ab-312) Antibody and the same antibody preincubated with blocking peptide.)

Related Product Information for anti-MEF2A antibody

The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain

Product Categories/Family for anti-MEF2A antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 195972801
• NCBI GeneID: 4205
• NCBI Accession #: NP_001124398.1
• NCBI GenBank Nucleotide #: NM_001130926.1
• UniProt Accession #: Q02078; O43814; Q14223; Q14224; Q59GX4; Q7Z6C9; Q96D14; B4DFQ7; F6XG23
• Molecular Weight: 45,570 Da
• NCBI Official Full Name: myocyte-specific enhancer factor 2A isoform 2
• NCBI Official Synonym Full Names: myocyte enhancer factor 2A
• NCBI Official Symbol: MEF2A
• NCBI Official Synonym Symbols: mef2; ADCAD1; RSRFC4; RSRFC9
• NCBI Protein Information: myocyte-specific enhancer factor 2A
• UniProt Protein Name: Myocyte-specific enhancer factor 2A
• UniProt Gene Name: MEF2A
• UniProt Synonym Gene Names: MEF2
• UniProt Entry Name: MEF2A_HUMAN