ICC (Immunocytochemistry)
(Immunocytochemistry of MFN1 in A431 cells with MFN1 antibody at 5 μg/mL.)
Rabbit MFN1 Polyclonal Antibody | anti-MFN1 antibody
MFN1 Antibody
Gene Names
MFN1; hfzo1; hfzo2
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
MFN1 antibody is affinity chromatography purified via peptide column.
Synonyms
MFN1, Antibody; MFN1 Antibody; MFN1; hfzo1; hfzo2; Mitofusin-1; Fzo homolog; mitofusin 1; anti-MFN1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MFN1 antibody is human, mouse and rat reactive. MFN1 antibody is predicted to not cross-react with MFN2.
Purity/Purification
MFN1 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
741
Applicable Applications for anti-MFN1 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
MFN1 antibody was raised against a 17 amino acid peptide near the amino terminus of human MFN1.
Buffer
MFN1 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
MFN1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
ICC (Immunocytochemistry)
(Immunocytochemistry of MFN1 in A431 cells with MFN1 antibody at 5 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of MFN1 in A431 cells with MFN1 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of MFN1 in A431 cell lysate with MFN1 antibody at 1 μg/ml.)
WB (Western Blot)
(Western blot analysis of MFN1 in A431 cell lysate with MFN1 antibody at 1 μg/ml.)
Related Product Information for anti-MFN1 antibody
Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (1,2). MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development (3). When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane (4).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 82 kDa
Observed: 83 kDa
Observed: 83 kDa
NCBI Official Full Name
mitofusin-1
NCBI Official Synonym Full Names
mitofusin 1
NCBI Official Symbol
MFN1
NCBI Official Synonym Symbols
hfzo1; hfzo2
NCBI Protein Information
mitofusin-1; fzo homolog; transmembrane GTPase MFN1; putative transmembrane GTPase; mitochondrial transmembrane GTPase FZO-2; mitochondrial transmembrane GTPase Fzo-1
UniProt Protein Name
Mitofusin-1
UniProt Gene Name
MFN1
UniProt Entry Name
MFN1_HUMAN
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Product Notes
The MFN1 mfn1 (Catalog #AAA40776) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MFN1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MFN1 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the MFN1 mfn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MFN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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