WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using MKL1 at 1:1000 dilution.)
Rabbit MKL1 Polyclonal Antibody | anti-MKL1 antibody
MKL1 Rabbit Polyclonal Antibody
Gene Names
MKL1; MAL; BSAC; MRTF-A
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
MKL1, Antibody; MKL1 Rabbit Polyclonal Antibody; MKL1; BSAC; MAL; MRTF-A; anti-MKL1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Applicable Applications for anti-MKL1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant fusion protein of human MKL1 (NP_065882.1).
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using MKL1 at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using MKL1 at 1:1000 dilution.)
IF (Immunofluorescence)
(Immunofluorescence analysis of U-2 OS cells using MKL1 Polyclonal at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of U-2 OS cells using MKL1 Polyclonal at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.)
Related Product Information for anti-MKL1 antibody
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-MKL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
98,919 Da
NCBI Official Full Name
MKL/myocardin-like protein 1
NCBI Official Synonym Full Names
megakaryoblastic leukemia (translocation) 1
NCBI Official Symbol
MKL1
NCBI Official Synonym Symbols
MAL; BSAC; MRTF-A
NCBI Protein Information
MKL/myocardin-like protein 1; basic, SAP and coiled-coil domain; megakaryoblastic leukemia 1 protein; megakaryocytic acute leukemia protein; myocardin-related transcription factor A; RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein
UniProt Protein Name
MKL/myocardin-like protein 1
UniProt Gene Name
MKL1
UniProt Synonym Gene Names
KIAA1438; MAL; MRTF-A
UniProt Entry Name
MKL1_HUMAN
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Product Notes
The MKL1 mkl1 (Catalog #AAA313486) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MKL1 Rabbit Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MKL1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MKL1 mkl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MKL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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