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product-image-AAA306260_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemical analysis of paraffin-embedded rat lung using MLST8 antibody at dilution of 1:200 (400x lens).)

Rabbit MLST8 Polyclonal Antibody | anti-MLST8 antibody

MLST8 Antibody

Gene Names
MLST8; GBL; LST8; POP3; WAT1; GbetaL
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
MLST8, Antibody; MLST8 Antibody; GBL; LST8; MGC111011; POP3; WAT1; anti-MLST8 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total MLST8 protein.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
326
Applicable Applications for anti-MLST8 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human MLST8.
Target Name
MLST8
Preparation and Storage
Store at -20 degree C

IHC (Immunohistochemisry)

(Immunohistochemical analysis of paraffin-embedded rat lung using MLST8 antibody at dilution of 1:200 (400x lens).)

product-image-AAA306260_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemical analysis of paraffin-embedded rat lung using MLST8 antibody at dilution of 1:200 (400x lens).)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded rat testis using MLST8 antibody at dilution of 1:200 (400x lens).)

product-image-AAA306260_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemical analysis of paraffin-embedded rat testis using MLST8 antibody at dilution of 1:200 (400x lens).)

WB (Western Blot)

(Western blot analysis of extracts of various cell lines, using MLST8 antibody.)

product-image-AAA306260_WB15.jpg WB (Western Blot) (Western blot analysis of extracts of various cell lines, using MLST8 antibody.)
Related Product Information for anti-MLST8 antibody
Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian Target of Rapamycin (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals (1). mTOR is a large protein kinase with two different complexes. One complex contains mTOR, GbL, and raptor, which is a target of rapamycin. The other complex, insensitive to rapamycin, includes mTOR, GbL, and rictor (1). GbL associates with the kinase domain of mTOR and stimulates mTOR kinase activity (2). A reduction in GbL expression has been shown to decrease in vivo phosphorylation of S6K1 (2).
Product Categories/Family for anti-MLST8 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,748 Da
NCBI Official Full Name
target of rapamycin complex subunit LST8 isoform a
NCBI Official Synonym Full Names
MTOR associated protein, LST8 homolog
NCBI Official Symbol
MLST8
NCBI Official Synonym Symbols
GBL; LST8; POP3; WAT1; GbetaL
NCBI Protein Information
target of rapamycin complex subunit LST8
UniProt Protein Name
Target of rapamycin complex subunit LST8
UniProt Gene Name
MLST8
UniProt Synonym Gene Names
GBL; LST8; TORC subunit LST8; Gable; Protein GbetaL; mLST8
UniProt Entry Name
LST8_HUMAN

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Product Notes

The MLST8 mlst8 (Catalog #AAA306260) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MLST8 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MLST8 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MLST8 mlst8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MLST8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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